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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC5
All Species:
14.55
Human Site:
S25
Identified Species:
29.09
UniProt:
Q8IY18
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY18
NP_055925.2
1101
128806
S25
R
A
L
P
R
D
P
S
S
E
V
P
S
K
R
Chimpanzee
Pan troglodytes
XP_520066
1204
140399
S128
R
A
L
P
R
D
P
S
S
E
V
P
S
K
R
Rhesus Macaque
Macaca mulatta
XP_001090492
1156
134111
S125
R
A
L
P
R
D
P
S
S
E
V
P
S
K
R
Dog
Lupus familis
XP_533529
1091
127678
P29
R
D
P
S
S
E
V
P
S
K
R
K
S
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8CG46
1101
128795
S25
R
S
L
P
R
D
A
S
S
E
V
P
S
K
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505381
1083
126056
G26
R
K
Q
P
S
A
G
G
S
Q
V
P
G
A
R
Chicken
Gallus gallus
Q5ZJY5
1065
124905
V28
H
A
G
K
P
R
S
V
E
G
S
I
V
R
I
Frog
Xenopus laevis
Q805A1
1065
124908
V27
Q
E
H
H
R
N
L
V
E
G
S
I
V
R
I
Zebra Danio
Brachydanio rerio
NP_001071040
697
80073
Tiger Blowfish
Takifugu rubipres
NP_001027801
1092
127634
S27
S
N
I
G
K
I
L
S
G
H
R
P
C
G
A
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786593
1069
124830
M26
D
Y
S
Q
D
G
Y
M
V
G
A
I
I
R
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08204
1093
126019
K31
S
K
R
V
K
I
A
K
P
D
L
S
S
F
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.9
89.8
92.1
N.A.
89.6
N.A.
N.A.
67.3
61.1
61.5
39.1
52.9
N.A.
N.A.
N.A.
38.1
Protein Similarity:
100
91.1
90.6
95.6
N.A.
95.8
N.A.
N.A.
81.4
77.3
76.8
49.7
71.6
N.A.
N.A.
N.A.
59.5
P-Site Identity:
100
100
100
20
N.A.
86.6
N.A.
N.A.
40
6.6
6.6
0
13.3
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
33.3
N.A.
93.3
N.A.
N.A.
46.6
13.3
26.6
0
26.6
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
34
0
0
0
9
17
0
0
0
9
0
0
9
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
9
9
0
0
9
34
0
0
0
9
0
0
0
0
0
% D
% Glu:
0
9
0
0
0
9
0
0
17
34
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
0
9
9
0
9
9
9
9
25
0
0
9
9
0
% G
% His:
9
0
9
9
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
17
0
0
0
0
0
25
9
0
25
% I
% Lys:
0
17
0
9
17
0
0
9
0
9
0
9
0
34
0
% K
% Leu:
0
0
34
0
0
0
17
0
0
0
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
9
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
9
42
9
0
25
9
9
0
0
50
0
0
0
% P
% Gln:
9
0
9
9
0
0
0
0
0
9
0
0
0
0
9
% Q
% Arg:
50
0
9
0
42
9
0
0
0
0
17
0
0
25
42
% R
% Ser:
17
9
9
9
17
0
9
42
50
0
17
9
50
9
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
9
0
0
9
17
9
0
42
0
17
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _