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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC5
All Species:
9.7
Human Site:
S35
Identified Species:
19.39
UniProt:
Q8IY18
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY18
NP_055925.2
1101
128806
S35
V
P
S
K
R
K
N
S
A
P
Q
L
P
L
L
Chimpanzee
Pan troglodytes
XP_520066
1204
140399
S138
V
P
S
K
R
K
N
S
A
P
Q
L
P
L
L
Rhesus Macaque
Macaca mulatta
XP_001090492
1156
134111
P135
V
P
S
K
R
K
N
P
A
P
Q
L
P
L
V
Dog
Lupus familis
XP_533529
1091
127678
A39
R
K
S
S
A
P
P
A
P
P
P
P
P
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8CG46
1101
128795
S35
V
P
S
K
R
K
N
S
N
P
L
P
T
L
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505381
1083
126056
R36
V
P
G
A
R
R
S
R
R
P
P
S
P
K
W
Chicken
Gallus gallus
Q5ZJY5
1065
124905
E38
S
I
V
R
I
Y
M
E
N
F
L
T
Y
D
I
Frog
Xenopus laevis
Q805A1
1065
124908
E37
S
I
V
R
I
K
M
E
N
F
L
T
Y
D
Q
Zebra Danio
Brachydanio rerio
NP_001071040
697
80073
Tiger Blowfish
Takifugu rubipres
NP_001027801
1092
127634
E37
R
P
C
G
A
E
V
E
G
R
M
D
G
S
I
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786593
1069
124830
V36
A
I
I
R
I
K
M
V
N
F
V
T
Y
D
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08204
1093
126019
S41
L
S
S
F
Q
P
G
S
I
I
K
I
R
L
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.9
89.8
92.1
N.A.
89.6
N.A.
N.A.
67.3
61.1
61.5
39.1
52.9
N.A.
N.A.
N.A.
38.1
Protein Similarity:
100
91.1
90.6
95.6
N.A.
95.8
N.A.
N.A.
81.4
77.3
76.8
49.7
71.6
N.A.
N.A.
N.A.
59.5
P-Site Identity:
100
100
86.6
26.6
N.A.
66.6
N.A.
N.A.
33.3
0
6.6
0
6.6
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
33.3
N.A.
66.6
N.A.
N.A.
46.6
13.3
13.3
0
20
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
17
0
0
9
25
0
0
0
0
0
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
9
0
25
0
% D
% Glu:
0
0
0
0
0
9
0
25
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
9
0
0
0
0
0
25
0
0
0
0
0
% F
% Gly:
0
0
9
9
0
0
9
0
9
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
25
9
0
25
0
0
0
9
9
0
9
0
0
17
% I
% Lys:
0
9
0
34
0
50
0
0
0
0
9
0
0
9
0
% K
% Leu:
9
0
0
0
0
0
0
0
0
0
25
25
0
42
25
% L
% Met:
0
0
0
0
0
0
25
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
34
0
34
0
0
0
0
0
0
% N
% Pro:
0
50
0
0
0
17
9
9
9
50
17
17
42
9
9
% P
% Gln:
0
0
0
0
9
0
0
0
0
0
25
0
0
0
17
% Q
% Arg:
17
0
0
25
42
9
0
9
9
9
0
0
9
0
0
% R
% Ser:
17
9
50
9
0
0
9
34
0
0
0
9
0
9
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
25
9
0
0
% T
% Val:
42
0
17
0
0
0
9
9
0
0
9
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
25
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _