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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC5
All Species:
23.64
Human Site:
S980
Identified Species:
47.27
UniProt:
Q8IY18
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY18
NP_055925.2
1101
128806
S980
I
R
V
K
F
R
S
S
T
Q
L
H
E
L
T
Chimpanzee
Pan troglodytes
XP_520066
1204
140399
S1083
I
R
V
K
F
R
S
S
T
Q
L
H
E
L
T
Rhesus Macaque
Macaca mulatta
XP_001090492
1156
134111
S1035
I
R
V
K
F
R
S
S
T
Q
L
H
E
L
T
Dog
Lupus familis
XP_533529
1091
127678
S969
I
R
V
K
F
R
S
S
T
Q
L
H
E
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8CG46
1101
128795
S980
I
R
V
K
F
R
S
S
T
Q
L
H
E
L
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505381
1083
126056
N961
I
R
V
K
F
R
S
N
S
K
L
H
E
L
T
Chicken
Gallus gallus
Q5ZJY5
1065
124905
F944
I
R
V
K
F
H
N
F
T
D
L
H
E
L
T
Frog
Xenopus laevis
Q805A1
1065
124908
S945
I
R
V
K
F
R
S
S
T
Q
L
H
E
L
T
Zebra Danio
Brachydanio rerio
NP_001071040
697
80073
T599
G
G
E
R
S
V
T
T
M
L
Y
L
M
S
L
Tiger Blowfish
Takifugu rubipres
NP_001027801
1092
127634
N973
I
R
V
K
F
H
S
N
T
Q
L
H
E
L
T
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786593
1069
124830
N947
I
K
V
K
F
R
R
N
E
Q
L
Q
L
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08204
1093
126019
N975
I
M
V
K
F
R
D
N
A
P
L
K
K
L
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.9
89.8
92.1
N.A.
89.6
N.A.
N.A.
67.3
61.1
61.5
39.1
52.9
N.A.
N.A.
N.A.
38.1
Protein Similarity:
100
91.1
90.6
95.6
N.A.
95.8
N.A.
N.A.
81.4
77.3
76.8
49.7
71.6
N.A.
N.A.
N.A.
59.5
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
80
73.3
100
0
86.6
N.A.
N.A.
N.A.
60
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
80
100
20
93.3
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
0
9
0
0
0
0
9
% D
% Glu:
0
0
9
0
0
0
0
0
9
0
0
0
75
0
0
% E
% Phe:
0
0
0
0
92
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
9
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
17
0
0
0
0
0
75
0
0
0
% H
% Ile:
92
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
0
92
0
0
0
0
0
9
0
9
9
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
9
92
9
9
92
9
% L
% Met:
0
9
0
0
0
0
0
0
9
0
0
0
9
0
0
% M
% Asn:
0
0
0
0
0
0
9
34
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
67
0
9
0
0
0
% Q
% Arg:
0
75
0
9
0
75
9
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
9
0
67
50
9
0
0
0
0
9
0
% S
% Thr:
0
0
0
0
0
0
9
9
67
0
0
0
0
0
84
% T
% Val:
0
0
92
0
0
9
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _