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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC5
All Species:
8.79
Human Site:
T10
Identified Species:
17.58
UniProt:
Q8IY18
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY18
NP_055925.2
1101
128806
T10
T
P
S
K
K
T
S
T
P
S
P
Q
P
S
K
Chimpanzee
Pan troglodytes
XP_520066
1204
140399
T113
T
P
S
K
K
T
S
T
P
S
P
Q
P
S
K
Rhesus Macaque
Macaca mulatta
XP_001090492
1156
134111
T110
T
P
S
K
K
T
S
T
P
S
P
Q
A
S
K
Dog
Lupus familis
XP_533529
1091
127678
V14
K
S
S
T
P
G
T
V
A
S
K
R
A
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8CG46
1101
128795
P10
T
P
S
G
K
A
A
P
P
N
P
Q
V
S
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505381
1083
126056
P11
P
A
K
R
K
P
G
P
A
E
E
P
P
I
P
Chicken
Gallus gallus
Q5ZJY5
1065
124905
Q13
R
L
R
A
E
G
S
Q
L
R
L
C
D
T
H
Frog
Xenopus laevis
Q805A1
1065
124908
G12
P
V
K
R
K
A
X
G
T
K
L
L
L
G
R
Zebra Danio
Brachydanio rerio
NP_001071040
697
80073
Tiger Blowfish
Takifugu rubipres
NP_001027801
1092
127634
R12
E
K
K
R
R
I
S
R
V
N
S
S
Q
T
S
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786593
1069
124830
A11
S
K
A
K
K
K
E
A
A
R
K
F
M
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08204
1093
126019
H16
R
Y
V
E
R
T
H
H
G
E
D
T
E
P
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.9
89.8
92.1
N.A.
89.6
N.A.
N.A.
67.3
61.1
61.5
39.1
52.9
N.A.
N.A.
N.A.
38.1
Protein Similarity:
100
91.1
90.6
95.6
N.A.
95.8
N.A.
N.A.
81.4
77.3
76.8
49.7
71.6
N.A.
N.A.
N.A.
59.5
P-Site Identity:
100
100
93.3
13.3
N.A.
60
N.A.
N.A.
13.3
6.6
6.6
0
6.6
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
93.3
26.6
N.A.
73.3
N.A.
N.A.
20
20
20
0
33.3
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
9
0
17
9
9
25
0
0
0
17
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% D
% Glu:
9
0
0
9
9
0
9
0
0
17
9
0
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
0
0
0
9
0
17
9
9
9
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
9
9
0
0
0
0
0
0
9
% H
% Ile:
0
0
0
0
0
9
0
0
0
0
0
0
0
9
0
% I
% Lys:
9
17
25
34
59
9
0
0
0
9
17
0
0
0
42
% K
% Leu:
0
9
0
0
0
0
0
0
9
0
17
9
9
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% N
% Pro:
17
34
0
0
9
9
0
17
34
0
34
9
25
9
17
% P
% Gln:
0
0
0
0
0
0
0
9
0
0
0
34
9
0
0
% Q
% Arg:
17
0
9
25
17
0
0
9
0
17
0
9
0
0
17
% R
% Ser:
9
9
42
0
0
0
42
0
0
34
9
9
0
42
9
% S
% Thr:
34
0
0
9
0
34
9
25
9
0
0
9
0
17
0
% T
% Val:
0
9
9
0
0
0
0
9
9
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _