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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC5
All Species:
25.76
Human Site:
T307
Identified Species:
51.52
UniProt:
Q8IY18
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY18
NP_055925.2
1101
128806
T307
K
E
G
Q
I
P
V
T
C
R
I
E
E
M
E
Chimpanzee
Pan troglodytes
XP_520066
1204
140399
T410
K
E
G
Q
I
P
I
T
R
R
I
E
E
M
E
Rhesus Macaque
Macaca mulatta
XP_001090492
1156
134111
T407
K
E
G
Q
I
P
I
T
R
R
I
E
E
M
E
Dog
Lupus familis
XP_533529
1091
127678
T311
K
E
G
Q
I
P
M
T
R
R
I
E
E
I
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CG46
1101
128795
T307
K
E
G
Q
I
P
M
T
R
R
I
E
E
I
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505381
1083
126056
T303
K
E
A
Q
F
P
L
T
Q
K
I
S
E
I
D
Chicken
Gallus gallus
Q5ZJY5
1065
124905
T286
K
E
M
Q
S
P
L
T
K
K
I
R
E
C
E
Frog
Xenopus laevis
Q805A1
1065
124908
N287
Q
G
L
Q
A
P
L
N
Q
K
I
Q
Q
I
E
Zebra Danio
Brachydanio rerio
NP_001071040
697
80073
M47
G
A
I
V
R
I
A
M
H
N
F
L
T
Y
D
Tiger Blowfish
Takifugu rubipres
NP_001027801
1092
127634
I298
R
H
S
Q
A
P
M
I
R
K
I
K
E
I
E
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786593
1069
124830
S301
L
Q
A
A
V
K
T
S
K
Q
L
D
Q
Q
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08204
1093
126019
R297
E
R
A
K
A
N
L
R
A
I
L
K
D
K
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.9
89.8
92.1
N.A.
89.6
N.A.
N.A.
67.3
61.1
61.5
39.1
52.9
N.A.
N.A.
N.A.
38.1
Protein Similarity:
100
91.1
90.6
95.6
N.A.
95.8
N.A.
N.A.
81.4
77.3
76.8
49.7
71.6
N.A.
N.A.
N.A.
59.5
P-Site Identity:
100
86.6
86.6
80
N.A.
73.3
N.A.
N.A.
46.6
53.3
26.6
0
33.3
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
93.3
N.A.
N.A.
73.3
66.6
66.6
6.6
66.6
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
25
9
25
0
9
0
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
25
% D
% Glu:
9
59
0
0
0
0
0
0
0
0
0
42
67
0
59
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
9
9
42
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
42
9
17
9
0
9
75
0
0
42
0
% I
% Lys:
59
0
0
9
0
9
0
0
17
34
0
17
0
9
17
% K
% Leu:
9
0
9
0
0
0
34
0
0
0
17
9
0
0
0
% L
% Met:
0
0
9
0
0
0
25
9
0
0
0
0
0
25
0
% M
% Asn:
0
0
0
0
0
9
0
9
0
9
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
75
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
9
0
75
0
0
0
0
17
9
0
9
17
9
0
% Q
% Arg:
9
9
0
0
9
0
0
9
42
42
0
9
0
0
0
% R
% Ser:
0
0
9
0
9
0
0
9
0
0
0
9
0
0
0
% S
% Thr:
0
0
0
0
0
0
9
59
0
0
0
0
9
0
0
% T
% Val:
0
0
0
9
9
0
9
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _