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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC5
All Species:
21.52
Human Site:
T798
Identified Species:
43.03
UniProt:
Q8IY18
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY18
NP_055925.2
1101
128806
T798
A
S
S
Q
L
R
L
T
E
Q
H
F
I
E
L
Chimpanzee
Pan troglodytes
XP_520066
1204
140399
T901
A
S
S
Q
L
R
L
T
E
Q
H
F
I
E
L
Rhesus Macaque
Macaca mulatta
XP_001090492
1156
134111
T853
A
S
S
Q
L
R
L
T
E
Q
H
F
I
E
L
Dog
Lupus familis
XP_533529
1091
127678
T802
A
S
S
Q
L
R
I
T
E
Q
H
F
I
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8CG46
1101
128795
T798
S
S
S
Q
L
R
V
T
E
Q
Q
F
I
E
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505381
1083
126056
L794
R
S
S
Q
L
Y
M
L
E
Q
Q
Y
V
A
L
Chicken
Gallus gallus
Q5ZJY5
1065
124905
S777
A
S
V
E
L
R
A
S
E
Q
R
F
L
E
L
Frog
Xenopus laevis
Q805A1
1065
124908
L778
A
T
S
Q
L
R
E
L
K
N
Q
Y
D
G
I
Zebra Danio
Brachydanio rerio
NP_001071040
697
80073
G445
E
I
C
N
M
T
P
G
E
T
A
V
P
E
E
Tiger Blowfish
Takifugu rubipres
NP_001027801
1092
127634
M789
G
A
S
L
L
R
S
M
D
Q
R
C
S
Q
L
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786593
1069
124830
Q783
T
K
N
E
I
G
I
Q
E
N
L
C
Q
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08204
1093
126019
L810
F
N
E
R
E
A
D
L
K
S
Q
Y
E
D
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.9
89.8
92.1
N.A.
89.6
N.A.
N.A.
67.3
61.1
61.5
39.1
52.9
N.A.
N.A.
N.A.
38.1
Protein Similarity:
100
91.1
90.6
95.6
N.A.
95.8
N.A.
N.A.
81.4
77.3
76.8
49.7
71.6
N.A.
N.A.
N.A.
59.5
P-Site Identity:
100
100
100
93.3
N.A.
80
N.A.
N.A.
46.6
60
33.3
13.3
33.3
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
93.3
N.A.
N.A.
66.6
80
60
20
53.3
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
9
0
0
0
9
9
0
0
0
9
0
0
9
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
17
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
9
0
0
0
9
9
0
% D
% Glu:
9
0
9
17
9
0
9
0
75
0
0
0
9
67
9
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
50
0
0
0
% F
% Gly:
9
0
0
0
0
9
0
9
0
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
34
0
0
0
0
% H
% Ile:
0
9
0
0
9
0
17
0
0
0
0
0
42
0
9
% I
% Lys:
0
9
0
0
0
0
0
0
17
0
0
0
0
0
9
% K
% Leu:
0
0
0
9
75
0
25
25
0
0
9
0
9
0
75
% L
% Met:
0
0
0
0
9
0
9
9
0
0
0
0
0
0
0
% M
% Asn:
0
9
9
9
0
0
0
0
0
17
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
9
0
0
0
0
0
9
0
0
% P
% Gln:
0
0
0
59
0
0
0
9
0
67
34
0
9
9
0
% Q
% Arg:
9
0
0
9
0
67
0
0
0
0
17
0
0
0
0
% R
% Ser:
9
59
67
0
0
0
9
9
0
9
0
0
9
0
0
% S
% Thr:
9
9
0
0
0
9
0
42
0
9
0
0
0
0
0
% T
% Val:
0
0
9
0
0
0
9
0
0
0
0
9
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
25
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _