KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC5
All Species:
24.55
Human Site:
Y235
Identified Species:
49.09
UniProt:
Q8IY18
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY18
NP_055925.2
1101
128806
Y235
S
C
K
E
K
T
E
Y
L
Q
K
M
V
Q
R
Chimpanzee
Pan troglodytes
XP_520066
1204
140399
Y338
S
C
K
E
K
T
E
Y
L
Q
K
M
V
Q
R
Rhesus Macaque
Macaca mulatta
XP_001090492
1156
134111
Y335
S
C
K
E
K
T
E
Y
L
Q
K
M
V
Q
R
Dog
Lupus familis
XP_533529
1091
127678
Y239
S
C
K
E
K
T
E
Y
L
E
K
M
I
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CG46
1101
128795
Y235
S
C
K
E
K
T
E
Y
L
E
K
M
V
Q
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505381
1083
126056
F231
S
Y
K
E
K
N
N
F
L
D
K
M
K
H
Q
Chicken
Gallus gallus
Q5ZJY5
1065
124905
S214
V
C
K
D
K
V
N
S
L
E
K
M
K
Q
R
Frog
Xenopus laevis
Q805A1
1065
124908
F215
A
C
K
S
K
A
E
F
L
E
K
L
N
Q
R
Zebra Danio
Brachydanio rerio
NP_001071040
697
80073
Tiger Blowfish
Takifugu rubipres
NP_001027801
1092
127634
Y226
T
V
T
E
K
T
K
Y
I
E
K
A
K
Q
R
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786593
1069
124830
H219
H
L
K
D
K
S
D
H
L
E
K
L
K
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08204
1093
126019
H238
F
K
K
A
K
I
V
H
L
R
Q
E
S
D
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.9
89.8
92.1
N.A.
89.6
N.A.
N.A.
67.3
61.1
61.5
39.1
52.9
N.A.
N.A.
N.A.
38.1
Protein Similarity:
100
91.1
90.6
95.6
N.A.
95.8
N.A.
N.A.
81.4
77.3
76.8
49.7
71.6
N.A.
N.A.
N.A.
59.5
P-Site Identity:
100
100
100
86.6
N.A.
93.3
N.A.
N.A.
46.6
53.3
53.3
0
46.6
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
60
66.6
80
0
73.3
N.A.
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
0
9
0
0
0
0
0
9
0
0
0
% A
% Cys:
0
59
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
17
0
0
9
0
0
9
0
0
0
9
0
% D
% Glu:
0
0
0
59
0
0
50
0
0
50
0
9
0
0
0
% E
% Phe:
9
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
9
0
0
0
0
0
0
17
0
0
0
0
0
9
0
% H
% Ile:
0
0
0
0
0
9
0
0
9
0
0
0
9
0
0
% I
% Lys:
0
9
84
0
92
0
9
0
0
0
84
0
34
0
9
% K
% Leu:
0
9
0
0
0
0
0
0
84
0
0
17
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
59
0
0
0
% M
% Asn:
0
0
0
0
0
9
17
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
25
9
0
0
75
17
% Q
% Arg:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
67
% R
% Ser:
50
0
0
9
0
9
0
9
0
0
0
0
9
0
0
% S
% Thr:
9
0
9
0
0
50
0
0
0
0
0
0
0
0
0
% T
% Val:
9
9
0
0
0
9
9
0
0
0
0
0
34
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _