KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC5
All Species:
28.48
Human Site:
Y613
Identified Species:
56.97
UniProt:
Q8IY18
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY18
NP_055925.2
1101
128806
Y613
E
T
R
L
K
Q
I
Y
T
A
E
E
K
Y
V
Chimpanzee
Pan troglodytes
XP_520066
1204
140399
Y716
E
T
R
L
K
Q
I
Y
T
A
E
E
K
Y
V
Rhesus Macaque
Macaca mulatta
XP_001090492
1156
134111
Q683
V
M
S
Y
L
C
C
Q
Y
H
I
H
E
V
P
Dog
Lupus familis
XP_533529
1091
127678
Y617
E
T
R
L
K
Q
M
Y
T
A
E
E
K
Y
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8CG46
1101
128795
Y613
E
T
R
L
K
Q
I
Y
T
A
E
E
K
Y
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505381
1083
126056
Y609
E
T
N
L
K
Q
I
Y
T
A
E
E
K
Y
S
Chicken
Gallus gallus
Q5ZJY5
1065
124905
Y592
E
T
K
L
K
Q
I
Y
T
A
E
E
K
Y
T
Frog
Xenopus laevis
Q805A1
1065
124908
Y593
E
T
D
L
R
Q
M
Y
T
A
E
E
K
Y
V
Zebra Danio
Brachydanio rerio
NP_001071040
697
80073
R277
E
Q
L
R
A
A
E
R
Q
K
Q
S
I
D
Q
Tiger Blowfish
Takifugu rubipres
NP_001027801
1092
127634
F604
E
L
N
L
R
V
L
F
T
L
D
E
R
Y
M
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786593
1069
124830
Y596
H
A
Q
V
N
K
F
Y
T
P
K
Y
Q
Y
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08204
1093
126019
H616
I
L
F
K
R
I
I
H
G
N
R
L
V
D
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.9
89.8
92.1
N.A.
89.6
N.A.
N.A.
67.3
61.1
61.5
39.1
52.9
N.A.
N.A.
N.A.
38.1
Protein Similarity:
100
91.1
90.6
95.6
N.A.
95.8
N.A.
N.A.
81.4
77.3
76.8
49.7
71.6
N.A.
N.A.
N.A.
59.5
P-Site Identity:
100
100
0
93.3
N.A.
100
N.A.
N.A.
86.6
86.6
80
6.6
33.3
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
6.6
100
N.A.
100
N.A.
N.A.
86.6
93.3
93.3
13.3
73.3
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
9
0
0
0
59
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
0
0
0
0
0
9
0
0
17
0
% D
% Glu:
75
0
0
0
0
0
9
0
0
0
59
67
9
0
0
% E
% Phe:
0
0
9
0
0
0
9
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% G
% His:
9
0
0
0
0
0
0
9
0
9
0
9
0
0
0
% H
% Ile:
9
0
0
0
0
9
50
0
0
0
9
0
9
0
9
% I
% Lys:
0
0
9
9
50
9
0
0
0
9
9
0
59
0
0
% K
% Leu:
0
17
9
67
9
0
9
0
0
9
0
9
0
0
0
% L
% Met:
0
9
0
0
0
0
17
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
17
0
9
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% P
% Gln:
0
9
9
0
0
59
0
9
9
0
9
0
9
0
9
% Q
% Arg:
0
0
34
9
25
0
0
9
0
0
9
0
9
0
0
% R
% Ser:
0
0
9
0
0
0
0
0
0
0
0
9
0
0
9
% S
% Thr:
0
59
0
0
0
0
0
0
75
0
0
0
0
0
17
% T
% Val:
9
0
0
9
0
9
0
0
0
0
0
0
9
9
42
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
67
9
0
0
9
0
75
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _