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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPAPDC2
All Species:
24.85
Human Site:
Y208
Identified Species:
60.74
UniProt:
Q8IY26
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY26
NP_982278.3
295
32194
Y208
V
T
L
S
V
D
K
Y
S
F
P
S
G
H
A
Chimpanzee
Pan troglodytes
XP_001137447
300
32428
Y213
V
T
L
S
V
D
K
Y
S
F
P
S
G
H
A
Rhesus Macaque
Macaca mulatta
XP_001085573
296
32254
Y209
V
T
L
S
V
D
K
Y
S
F
P
S
G
H
A
Dog
Lupus familis
XP_851974
204
22987
V130
H
A
T
R
A
A
L
V
S
R
F
I
L
N
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9D4F2
292
31726
Y205
F
T
L
S
V
D
R
Y
S
F
P
S
G
H
A
Rat
Rattus norvegicus
Q66H88
293
31682
Y206
F
T
L
S
V
D
K
Y
S
F
P
S
G
H
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415460
271
29827
Y187
D
Y
L
T
M
D
T
Y
A
F
P
A
G
H
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5TZ07
288
31266
Y203
A
T
F
S
V
D
S
Y
S
F
P
S
G
H
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_723543
204
22939
K130
F
V
L
L
F
F
A
K
L
Y
P
L
H
I
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169593
204
21351
H130
H
W
S
F
P
S
G
H
S
S
R
A
F
L
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
97.9
65
N.A.
87.8
88.4
N.A.
N.A.
42.7
N.A.
60.3
N.A.
26.7
N.A.
N.A.
N.A.
Protein Similarity:
100
98
98.6
66.7
N.A.
93.2
92.8
N.A.
N.A.
61.6
N.A.
71.5
N.A.
43
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
86.6
93.3
N.A.
N.A.
53.3
N.A.
80
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
93.3
93.3
N.A.
N.A.
80
N.A.
80
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
31.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
41
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
20
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
10
10
10
0
10
0
0
20
0
0
70
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
70
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
30
0
10
10
10
10
0
0
0
70
10
0
10
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
0
0
70
0
0
% G
% His:
20
0
0
0
0
0
0
10
0
0
0
0
10
70
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
10
% I
% Lys:
0
0
0
0
0
0
40
10
0
0
0
0
0
0
0
% K
% Leu:
0
0
70
10
0
0
10
0
10
0
0
10
10
10
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
10
0
0
0
0
0
80
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
0
10
0
0
10
10
0
0
0
0
% R
% Ser:
0
0
10
60
0
10
10
0
80
10
0
60
0
0
0
% S
% Thr:
0
60
10
10
0
0
10
0
0
0
0
0
0
0
0
% T
% Val:
30
10
0
0
60
0
0
10
0
0
0
0
0
0
10
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
70
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _