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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MICALL2
All Species:
7.27
Human Site:
S249
Identified Species:
14.55
UniProt:
Q8IY33
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY33
NP_891554.1
904
97502
S249
L
P
A
A
A
S
A
S
P
K
L
T
G
L
V
Chimpanzee
Pan troglodytes
XP_515124
889
95596
T255
G
P
G
T
R
S
G
T
R
P
G
P
F
S
Q
Rhesus Macaque
Macaca mulatta
XP_001100629
896
96258
K247
A
T
T
S
A
S
P
K
L
P
G
L
V
P
Q
Dog
Lupus familis
XP_547017
864
90740
S225
H
P
E
A
A
S
A
S
P
M
L
R
G
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGT6
870
94073
S226
C
T
R
L
G
P
G
S
R
S
G
T
R
L
L
Rat
Rattus norvegicus
XP_221956
1008
107848
S250
S
S
E
A
V
S
V
S
P
K
L
S
N
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414767
634
71328
N62
K
E
N
V
Y
E
N
N
K
L
A
F
Q
V
A
Frog
Xenopus laevis
NP_001085831
967
106450
L249
H
L
A
A
P
T
S
L
V
T
R
A
I
I
P
Zebra Danio
Brachydanio rerio
NP_963879
560
61176
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648621
1010
113828
P281
L
T
I
N
P
V
N
P
I
L
S
E
E
R
K
Honey Bee
Apis mellifera
XP_396410
883
101342
I252
E
S
V
D
K
E
N
I
T
K
T
N
D
Y
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001199595
1096
121855
A404
K
S
P
A
E
S
P
A
R
P
V
P
L
P
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.7
87.1
51.9
N.A.
33.6
53.7
N.A.
N.A.
40.4
38.3
27.3
N.A.
22.2
20.5
N.A.
27
Protein Similarity:
100
46.4
90.1
63.5
N.A.
47.9
63.5
N.A.
N.A.
53.3
54.1
39
N.A.
37.7
37.1
N.A.
43
P-Site Identity:
100
13.3
13.3
60
N.A.
20
46.6
N.A.
N.A.
0
13.3
0
N.A.
6.6
6.6
N.A.
13.3
P-Site Similarity:
100
20
20
60
N.A.
26.6
53.3
N.A.
N.A.
13.3
33.3
0
N.A.
6.6
6.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
17
42
25
0
17
9
0
0
9
9
0
0
25
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
0
0
9
0
9
% D
% Glu:
9
9
17
0
9
17
0
0
0
0
0
9
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% F
% Gly:
9
0
9
0
9
0
17
0
0
0
25
0
17
0
0
% G
% His:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
9
9
0
0
0
9
9
0
% I
% Lys:
17
0
0
0
9
0
0
9
9
25
0
0
0
0
9
% K
% Leu:
17
9
0
9
0
0
0
9
9
17
25
9
9
25
9
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
9
9
0
0
25
9
0
0
0
9
9
0
0
% N
% Pro:
0
25
9
0
17
9
17
9
25
25
0
17
0
25
9
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
17
% Q
% Arg:
0
0
9
0
9
0
0
0
25
0
9
9
9
9
9
% R
% Ser:
9
25
0
9
0
50
9
34
0
9
9
9
0
9
0
% S
% Thr:
0
25
9
9
0
9
0
9
9
9
9
17
0
0
0
% T
% Val:
0
0
9
9
9
9
9
0
9
0
9
0
9
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _