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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MICALL2
All Species:
7.88
Human Site:
S285
Identified Species:
15.76
UniProt:
Q8IY33
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY33
NP_891554.1
904
97502
S285
E
A
N
K
A
R
P
S
A
W
E
P
A
A
G
Chimpanzee
Pan troglodytes
XP_515124
889
95596
A291
S
S
S
A
P
A
G
A
E
A
D
G
P
K
A
Rhesus Macaque
Macaca mulatta
XP_001100629
896
96258
S283
N
K
P
K
A
R
P
S
A
W
E
P
A
A
G
Dog
Lupus familis
XP_547017
864
90740
A261
E
A
N
G
P
R
D
A
G
P
E
S
R
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGT6
870
94073
E262
L
S
V
A
A
V
A
E
A
D
R
L
Q
A
S
Rat
Rattus norvegicus
XP_221956
1008
107848
P286
E
T
N
G
E
A
T
P
L
R
A
R
T
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414767
634
71328
Y98
D
R
L
S
I
I
T
Y
V
S
Q
Y
Y
N
Y
Frog
Xenopus laevis
NP_001085831
967
106450
T285
V
H
D
Q
N
N
K
T
P
G
N
R
F
G
L
Zebra Danio
Brachydanio rerio
NP_963879
560
61176
S24
G
Y
R
D
V
A
I
S
N
M
S
M
S
F
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648621
1010
113828
P317
T
P
V
K
P
A
I
P
E
K
P
K
V
S
T
Honey Bee
Apis mellifera
XP_396410
883
101342
S288
F
D
S
V
T
D
K
S
L
C
E
S
N
D
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001199595
1096
121855
S440
T
G
L
S
T
T
E
S
S
S
E
D
S
K
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.7
87.1
51.9
N.A.
33.6
53.7
N.A.
N.A.
40.4
38.3
27.3
N.A.
22.2
20.5
N.A.
27
Protein Similarity:
100
46.4
90.1
63.5
N.A.
47.9
63.5
N.A.
N.A.
53.3
54.1
39
N.A.
37.7
37.1
N.A.
43
P-Site Identity:
100
0
80
33.3
N.A.
20
20
N.A.
N.A.
0
0
6.6
N.A.
6.6
13.3
N.A.
13.3
P-Site Similarity:
100
26.6
80
40
N.A.
26.6
20
N.A.
N.A.
13.3
20
13.3
N.A.
13.3
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
17
25
34
9
17
25
9
9
0
17
34
34
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
9
9
9
9
0
9
9
0
0
9
9
9
0
9
0
% D
% Glu:
25
0
0
0
9
0
9
9
17
0
42
0
0
0
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% F
% Gly:
9
9
0
17
0
0
9
0
9
9
0
9
0
9
17
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
9
17
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
0
25
0
0
17
0
0
9
0
9
0
17
9
% K
% Leu:
9
0
17
0
0
0
0
0
17
0
0
9
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
9
0
0
0
% M
% Asn:
9
0
25
0
9
9
0
0
9
0
9
0
9
9
0
% N
% Pro:
0
9
9
0
25
0
17
17
9
9
9
17
9
9
0
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
9
0
9
0
0
% Q
% Arg:
0
9
9
0
0
25
0
0
0
9
9
17
9
0
9
% R
% Ser:
9
17
17
17
0
0
0
42
9
17
9
17
17
9
9
% S
% Thr:
17
9
0
0
17
9
17
9
0
0
0
0
9
0
9
% T
% Val:
9
0
17
9
9
9
0
0
9
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
9
0
0
0
9
9
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _