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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MICALL2
All Species:
6.67
Human Site:
S397
Identified Species:
13.33
UniProt:
Q8IY33
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY33
NP_891554.1
904
97502
S397
T
L
S
S
S
S
T
S
A
A
T
V
D
P
P
Chimpanzee
Pan troglodytes
XP_515124
889
95596
A403
P
W
I
T
L
V
Q
A
E
P
K
K
K
P
A
Rhesus Macaque
Macaca mulatta
XP_001100629
896
96258
S395
T
V
S
S
S
S
T
S
A
A
T
V
D
P
P
Dog
Lupus familis
XP_547017
864
90740
G373
P
H
T
K
V
S
L
G
P
T
S
P
G
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGT6
870
94073
E374
W
I
T
L
V
Q
T
E
P
K
K
K
P
A
P
Rat
Rattus norvegicus
XP_221956
1008
107848
N398
K
G
V
K
T
Q
L
N
S
S
T
D
S
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414767
634
71328
C210
N
C
F
R
C
R
E
C
W
N
V
L
L
P
G
Frog
Xenopus laevis
NP_001085831
967
106450
P397
R
S
V
A
N
E
Q
P
K
K
P
S
T
D
L
Zebra Danio
Brachydanio rerio
NP_963879
560
61176
P136
P
S
E
K
K
N
L
P
V
V
A
K
N
H
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648621
1010
113828
S429
K
I
F
S
N
T
E
S
C
S
K
Q
E
G
V
Honey Bee
Apis mellifera
XP_396410
883
101342
L400
T
D
T
F
E
Q
S
L
P
H
A
T
E
I
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001199595
1096
121855
N552
N
E
D
I
S
V
A
N
K
E
K
D
K
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.7
87.1
51.9
N.A.
33.6
53.7
N.A.
N.A.
40.4
38.3
27.3
N.A.
22.2
20.5
N.A.
27
Protein Similarity:
100
46.4
90.1
63.5
N.A.
47.9
63.5
N.A.
N.A.
53.3
54.1
39
N.A.
37.7
37.1
N.A.
43
P-Site Identity:
100
6.6
93.3
13.3
N.A.
13.3
6.6
N.A.
N.A.
6.6
0
0
N.A.
13.3
6.6
N.A.
6.6
P-Site Similarity:
100
20
100
26.6
N.A.
26.6
33.3
N.A.
N.A.
13.3
13.3
13.3
N.A.
46.6
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
9
9
17
17
17
0
0
9
17
% A
% Cys:
0
9
0
0
9
0
0
9
9
0
0
0
0
0
0
% C
% Asp:
0
9
9
0
0
0
0
0
0
0
0
17
17
9
0
% D
% Glu:
0
9
9
0
9
9
17
9
9
9
0
0
17
9
9
% E
% Phe:
0
0
17
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
0
9
0
0
0
0
9
9
9
% G
% His:
0
9
0
0
0
0
0
0
0
9
0
0
0
9
0
% H
% Ile:
0
17
9
9
0
0
0
0
0
0
0
0
0
9
0
% I
% Lys:
17
0
0
25
9
0
0
0
17
17
34
25
17
0
0
% K
% Leu:
0
9
0
9
9
0
25
9
0
0
0
9
9
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
17
0
0
0
17
9
0
17
0
9
0
0
9
0
17
% N
% Pro:
25
0
0
0
0
0
0
17
25
9
9
9
9
42
25
% P
% Gln:
0
0
0
0
0
25
17
0
0
0
0
9
0
0
0
% Q
% Arg:
9
0
0
9
0
9
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
17
17
25
25
25
9
25
9
17
9
9
9
9
9
% S
% Thr:
25
0
25
9
9
9
25
0
0
9
25
9
9
0
0
% T
% Val:
0
9
17
0
17
17
0
0
9
9
9
17
0
0
9
% V
% Trp:
9
9
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _