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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MICALL2
All Species:
3.94
Human Site:
S542
Identified Species:
7.88
UniProt:
Q8IY33
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY33
NP_891554.1
904
97502
S542
G
R
R
N
L
A
E
S
S
G
V
G
R
V
G
Chimpanzee
Pan troglodytes
XP_515124
889
95596
T548
S
S
E
S
A
S
Q
T
A
G
A
E
L
L
E
Rhesus Macaque
Macaca mulatta
XP_001100629
896
96258
P540
G
R
R
S
L
A
K
P
S
G
V
G
R
V
G
Dog
Lupus familis
XP_547017
864
90740
P518
Q
V
D
K
K
D
P
P
V
S
S
G
A
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGT6
870
94073
L519
S
A
T
P
S
P
A
L
S
V
E
S
L
S
S
Rat
Rattus norvegicus
XP_221956
1008
107848
V543
T
S
K
A
S
T
V
V
T
V
P
T
G
R
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414767
634
71328
K355
H
K
D
Q
A
G
S
K
K
P
T
D
H
S
Q
Frog
Xenopus laevis
NP_001085831
967
106450
N542
K
P
S
G
E
A
E
N
P
S
P
V
Y
R
P
Zebra Danio
Brachydanio rerio
NP_963879
560
61176
D281
G
A
Y
K
L
G
S
D
T
G
S
L
V
C
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648621
1010
113828
I574
S
S
E
H
L
N
S
I
R
T
F
D
R
G
A
Honey Bee
Apis mellifera
XP_396410
883
101342
N545
I
K
H
D
E
G
I
N
V
T
E
R
Q
E
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001199595
1096
121855
T697
G
D
E
D
E
E
E
T
E
E
T
G
K
R
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.7
87.1
51.9
N.A.
33.6
53.7
N.A.
N.A.
40.4
38.3
27.3
N.A.
22.2
20.5
N.A.
27
Protein Similarity:
100
46.4
90.1
63.5
N.A.
47.9
63.5
N.A.
N.A.
53.3
54.1
39
N.A.
37.7
37.1
N.A.
43
P-Site Identity:
100
6.6
80
6.6
N.A.
6.6
6.6
N.A.
N.A.
0
13.3
20
N.A.
13.3
0
N.A.
20
P-Site Similarity:
100
46.6
93.3
6.6
N.A.
6.6
20
N.A.
N.A.
6.6
20
26.6
N.A.
20
26.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
9
17
25
9
0
9
0
9
0
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
9
17
17
0
9
0
9
0
0
0
17
0
0
0
% D
% Glu:
0
0
25
0
25
9
25
0
9
9
17
9
0
9
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
34
0
0
9
0
25
0
0
0
34
0
34
9
9
25
% G
% His:
9
0
9
9
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
9
0
0
0
0
0
9
9
0
0
0
0
0
0
0
% I
% Lys:
9
17
9
17
9
0
9
9
9
0
0
0
9
0
0
% K
% Leu:
0
0
0
0
34
0
0
9
0
0
0
9
17
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
9
0
17
0
0
0
0
0
0
0
% N
% Pro:
0
9
0
9
0
9
9
17
9
9
17
0
0
0
9
% P
% Gln:
9
0
0
9
0
0
9
0
0
0
0
0
9
0
17
% Q
% Arg:
0
17
17
0
0
0
0
0
9
0
0
9
25
25
9
% R
% Ser:
25
25
9
17
17
9
25
9
25
17
17
9
0
25
17
% S
% Thr:
9
0
9
0
0
9
0
17
17
17
17
9
0
0
9
% T
% Val:
0
9
0
0
0
0
9
9
17
17
17
9
9
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _