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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MICALL2
All Species:
6.67
Human Site:
S573
Identified Species:
13.33
UniProt:
Q8IY33
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY33
NP_891554.1
904
97502
S573
T
T
L
T
Q
D
M
S
T
S
L
Q
E
G
Q
Chimpanzee
Pan troglodytes
XP_515124
889
95596
S579
G
T
P
G
N
P
V
S
L
S
T
N
S
S
L
Rhesus Macaque
Macaca mulatta
XP_001100629
896
96258
S571
T
T
L
T
Q
D
G
S
A
S
P
Q
E
G
Q
Dog
Lupus familis
XP_547017
864
90740
G549
S
G
T
S
P
Q
E
G
Q
E
D
G
P
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGT6
870
94073
P550
V
P
K
S
S
S
D
P
A
V
H
V
P
G
T
Rat
Rattus norvegicus
XP_221956
1008
107848
R574
N
P
A
Q
E
S
S
R
E
Q
A
L
S
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414767
634
71328
E386
V
V
P
S
A
K
Q
E
S
A
S
S
G
G
I
Frog
Xenopus laevis
NP_001085831
967
106450
V573
K
V
E
P
V
R
P
V
P
K
E
R
K
I
K
Zebra Danio
Brachydanio rerio
NP_963879
560
61176
S312
K
S
S
G
F
T
V
S
D
L
V
A
K
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648621
1010
113828
G605
K
P
L
R
A
S
V
G
S
P
L
R
S
E
E
Honey Bee
Apis mellifera
XP_396410
883
101342
G576
P
E
S
N
I
R
I
G
G
T
Y
R
K
K
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001199595
1096
121855
D728
N
L
N
P
F
G
E
D
E
D
E
G
N
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.7
87.1
51.9
N.A.
33.6
53.7
N.A.
N.A.
40.4
38.3
27.3
N.A.
22.2
20.5
N.A.
27
Protein Similarity:
100
46.4
90.1
63.5
N.A.
47.9
63.5
N.A.
N.A.
53.3
54.1
39
N.A.
37.7
37.1
N.A.
43
P-Site Identity:
100
20
80
0
N.A.
6.6
0
N.A.
N.A.
6.6
0
6.6
N.A.
13.3
0
N.A.
0
P-Site Similarity:
100
26.6
80
13.3
N.A.
13.3
6.6
N.A.
N.A.
26.6
20
40
N.A.
40
33.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
17
0
0
0
17
9
9
9
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
17
9
9
9
9
9
0
0
0
0
% D
% Glu:
0
9
9
0
9
0
17
9
17
9
17
0
17
17
17
% E
% Phe:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
9
0
17
0
9
9
25
9
0
0
17
9
34
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
9
0
0
0
0
0
0
9
9
% I
% Lys:
25
0
9
0
0
9
0
0
0
9
0
0
25
9
17
% K
% Leu:
0
9
25
0
0
0
0
0
9
9
17
9
0
0
17
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
17
0
9
9
9
0
0
0
0
0
0
9
9
0
0
% N
% Pro:
9
25
17
17
9
9
9
9
9
9
9
0
17
0
0
% P
% Gln:
0
0
0
9
17
9
9
0
9
9
0
17
0
0
17
% Q
% Arg:
0
0
0
9
0
17
0
9
0
0
0
25
0
0
0
% R
% Ser:
9
9
17
25
9
25
9
34
17
25
9
9
25
17
9
% S
% Thr:
17
25
9
17
0
9
0
0
9
9
9
0
0
0
9
% T
% Val:
17
17
0
0
9
0
25
9
0
9
9
9
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _