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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC15A3
All Species:
14.24
Human Site:
S145
Identified Species:
26.11
UniProt:
Q8IY34
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY34
NP_057666.1
581
63560
S145
P
L
G
P
A
C
P
S
A
G
C
P
R
S
S
Chimpanzee
Pan troglodytes
XP_508467
527
57583
S100
G
C
P
R
S
S
P
S
P
Y
C
A
P
V
L
Rhesus Macaque
Macaca mulatta
XP_001084703
580
62690
S145
P
L
G
P
A
C
P
S
P
D
C
P
R
A
S
Dog
Lupus familis
XP_852542
566
61087
S134
P
T
R
L
R
N
C
S
A
P
P
C
P
D
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BPX9
578
64032
S145
P
L
E
P
A
C
P
S
S
S
C
Q
G
S
W
Rat
Rattus norvegicus
Q924V4
582
64575
S145
P
L
K
P
A
C
P
S
A
N
C
Q
G
S
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508474
657
71951
T193
K
L
R
A
G
S
K
T
L
T
R
N
D
Q
C
Chicken
Gallus gallus
XP_415099
492
54115
D100
N
I
T
P
F
G
A
D
Q
V
K
D
R
G
P
Frog
Xenopus laevis
Q68F72
569
63068
S148
C
S
R
S
N
A
S
S
D
D
T
C
P
E
P
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783351
614
68101
D160
T
I
H
P
E
G
H
D
L
G
P
A
P
M
K
Poplar Tree
Populus trichocarpa
XP_002315835
584
64173
S148
K
P
A
E
C
V
G
S
L
C
P
P
A
T
P
Maize
Zea mays
NP_001146682
587
64502
C147
P
M
L
M
P
P
S
C
E
G
S
F
C
P
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LFB8
570
63290
G129
G
L
T
P
T
C
S
G
E
T
C
H
A
T
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.5
88.6
50.5
N.A.
80.7
80.9
N.A.
35.6
43.8
48.1
N.A.
N.A.
N.A.
N.A.
N.A.
39.2
Protein Similarity:
100
89.8
91.3
66.9
N.A.
86.5
86.7
N.A.
50.8
58.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
54.5
P-Site Identity:
100
20
80
20
N.A.
60
66.6
N.A.
6.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
26.6
86.6
26.6
N.A.
66.6
66.6
N.A.
13.3
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
28
28.4
N.A.
25.8
N.A.
N.A.
Protein Similarity:
47.4
47.3
N.A.
46.3
N.A.
N.A.
P-Site Identity:
13.3
13.3
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
20
26.6
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
31
8
8
0
24
0
0
16
16
8
24
% A
% Cys:
8
8
0
0
8
39
8
8
0
8
47
16
8
0
8
% C
% Asp:
0
0
0
0
0
0
0
16
8
16
0
8
8
8
0
% D
% Glu:
0
0
8
8
8
0
0
0
16
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
16
0
16
0
8
16
8
8
0
24
0
0
16
8
0
% G
% His:
0
0
8
0
0
0
8
0
0
0
0
8
0
0
0
% H
% Ile:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
16
0
8
0
0
0
8
0
0
0
8
0
0
0
8
% K
% Leu:
0
47
8
8
0
0
0
0
24
0
0
0
0
0
8
% L
% Met:
0
8
0
8
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
8
0
0
0
8
8
0
0
0
8
0
8
0
0
0
% N
% Pro:
47
8
8
54
8
8
39
0
16
8
24
24
31
8
24
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
16
0
8
0
% Q
% Arg:
0
0
24
8
8
0
0
0
0
0
8
0
24
0
0
% R
% Ser:
0
8
0
8
8
16
24
62
8
8
8
0
0
24
16
% S
% Thr:
8
8
16
0
8
0
0
8
0
16
8
0
0
16
0
% T
% Val:
0
0
0
0
0
8
0
0
0
8
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _