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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC15A3
All Species:
17.88
Human Site:
S181
Identified Species:
32.78
UniProt:
Q8IY34
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY34
NP_057666.1
581
63560
S181
S
V
R
S
N
L
T
S
F
G
A
D
Q
V
M
Chimpanzee
Pan troglodytes
XP_508467
527
57583
L136
G
A
D
Q
V
M
D
L
G
R
D
A
T
R
R
Rhesus Macaque
Macaca mulatta
XP_001084703
580
62690
S181
S
V
R
S
N
L
T
S
F
G
A
D
Q
V
M
Dog
Lupus familis
XP_852542
566
61087
P170
A
V
K
A
N
V
T
P
F
G
A
D
Q
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BPX9
578
64032
S181
S
V
R
S
T
L
T
S
F
G
A
D
Q
V
M
Rat
Rattus norvegicus
Q924V4
582
64575
S181
S
V
R
S
N
L
T
S
F
G
A
D
Q
V
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508474
657
71951
T229
E
T
N
V
K
L
V
T
N
G
V
I
R
V
K
Chicken
Gallus gallus
XP_415099
492
54115
Q136
L
G
G
I
A
Y
I
Q
Q
N
V
S
F
V
I
Frog
Xenopus laevis
Q68F72
569
63068
P184
S
V
K
A
N
I
T
P
F
G
A
D
Q
V
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783351
614
68101
P196
S
V
R
A
N
L
S
P
F
G
A
E
Q
V
K
Poplar Tree
Populus trichocarpa
XP_002315835
584
64173
A184
P
C
V
S
S
F
G
A
D
Q
F
D
D
T
D
Maize
Zea mays
NP_001146682
587
64502
S183
G
I
K
P
C
V
S
S
F
G
A
D
Q
F
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LFB8
570
63290
A165
P
C
V
S
S
F
G
A
D
Q
F
D
D
T
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.5
88.6
50.5
N.A.
80.7
80.9
N.A.
35.6
43.8
48.1
N.A.
N.A.
N.A.
N.A.
N.A.
39.2
Protein Similarity:
100
89.8
91.3
66.9
N.A.
86.5
86.7
N.A.
50.8
58.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
54.5
P-Site Identity:
100
0
100
60
N.A.
93.3
100
N.A.
20
6.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
66.6
P-Site Similarity:
100
6.6
100
86.6
N.A.
93.3
100
N.A.
33.3
13.3
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
86.6
Percent
Protein Identity:
28
28.4
N.A.
25.8
N.A.
N.A.
Protein Similarity:
47.4
47.3
N.A.
46.3
N.A.
N.A.
P-Site Identity:
13.3
40
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
26.6
66.6
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
24
8
0
0
16
0
0
62
8
0
0
0
% A
% Cys:
0
16
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
8
0
16
0
8
70
16
0
24
% D
% Glu:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
16
0
0
62
0
16
0
8
8
0
% F
% Gly:
16
8
8
0
0
0
16
0
8
70
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
8
0
8
8
0
0
0
0
8
0
0
8
% I
% Lys:
0
0
24
0
8
0
0
0
0
0
0
0
0
0
31
% K
% Leu:
8
0
0
0
0
47
0
8
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
31
% M
% Asn:
0
0
8
0
47
0
0
0
8
8
0
0
0
0
0
% N
% Pro:
16
0
0
8
0
0
0
24
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
8
8
16
0
0
62
0
0
% Q
% Arg:
0
0
39
0
0
0
0
0
0
8
0
0
8
8
8
% R
% Ser:
47
0
0
47
16
0
16
39
0
0
0
8
0
0
0
% S
% Thr:
0
8
0
0
8
0
47
8
0
0
0
0
8
16
0
% T
% Val:
0
54
16
8
8
16
8
0
0
0
16
0
0
70
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _