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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC15A3
All Species:
31.82
Human Site:
S259
Identified Species:
58.33
UniProt:
Q8IY34
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY34
NP_057666.1
581
63560
S259
I
T
K
P
P
M
G
S
Q
V
S
S
M
L
K
Chimpanzee
Pan troglodytes
XP_508467
527
57583
K212
S
Q
V
S
S
M
L
K
L
A
L
Q
N
C
C
Rhesus Macaque
Macaca mulatta
XP_001084703
580
62690
S259
I
T
K
P
P
M
G
S
Q
V
S
S
M
L
K
Dog
Lupus familis
XP_852542
566
61087
S248
I
T
K
P
P
D
G
S
A
F
T
Y
M
F
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BPX9
578
64032
S259
I
T
K
P
P
T
G
S
Q
V
S
S
M
L
K
Rat
Rattus norvegicus
Q924V4
582
64575
S259
I
T
K
P
P
T
G
S
Q
V
S
S
M
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508474
657
71951
S307
I
S
K
P
P
D
G
S
A
F
T
D
M
F
K
Chicken
Gallus gallus
XP_415099
492
54115
Q212
V
L
Q
Q
P
R
K
Q
S
L
F
E
M
A
K
Frog
Xenopus laevis
Q68F72
569
63068
S262
V
T
K
P
A
D
G
S
A
F
T
D
M
V
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783351
614
68101
S274
L
I
K
D
P
T
G
S
V
L
P
N
T
F
K
Poplar Tree
Populus trichocarpa
XP_002315835
584
64173
S262
R
F
Q
R
P
G
G
S
P
I
T
R
M
C
Q
Maize
Zea mays
NP_001146682
587
64502
S264
R
F
Q
K
P
G
G
S
P
I
T
R
V
C
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LFB8
570
63290
S243
R
L
Q
K
P
G
G
S
P
L
T
R
M
L
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.5
88.6
50.5
N.A.
80.7
80.9
N.A.
35.6
43.8
48.1
N.A.
N.A.
N.A.
N.A.
N.A.
39.2
Protein Similarity:
100
89.8
91.3
66.9
N.A.
86.5
86.7
N.A.
50.8
58.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
54.5
P-Site Identity:
100
6.6
100
60
N.A.
93.3
86.6
N.A.
53.3
20
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
6.6
100
66.6
N.A.
93.3
86.6
N.A.
66.6
40
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
28
28.4
N.A.
25.8
N.A.
N.A.
Protein Similarity:
47.4
47.3
N.A.
46.3
N.A.
N.A.
P-Site Identity:
26.6
20
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
53.3
53.3
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
24
8
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
24
8
% C
% Asp:
0
0
0
8
0
24
0
0
0
0
0
16
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
16
0
0
0
0
0
0
0
24
8
0
0
24
0
% F
% Gly:
0
0
0
0
0
24
85
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
47
8
0
0
0
0
0
0
0
16
0
0
0
0
0
% I
% Lys:
0
0
62
16
0
0
8
8
0
0
0
0
0
0
62
% K
% Leu:
8
16
0
0
0
0
8
0
8
24
8
0
0
39
0
% L
% Met:
0
0
0
0
0
24
0
0
0
0
0
0
77
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
8
% N
% Pro:
0
0
0
54
85
0
0
0
24
0
8
0
0
0
0
% P
% Gln:
0
8
31
8
0
0
0
8
31
0
0
8
0
0
24
% Q
% Arg:
24
0
0
8
0
8
0
0
0
0
0
24
0
0
0
% R
% Ser:
8
8
0
8
8
0
0
85
8
0
31
31
0
0
0
% S
% Thr:
0
47
0
0
0
24
0
0
0
0
47
0
8
0
0
% T
% Val:
16
0
8
0
0
0
0
0
8
31
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _