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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC15A3
All Species:
13.03
Human Site:
S572
Identified Species:
23.89
UniProt:
Q8IY34
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY34
NP_057666.1
581
63560
S572
R
A
S
Q
G
P
A
S
H
S
R
F
S
R
D
Chimpanzee
Pan troglodytes
XP_508467
527
57583
S518
R
A
S
Q
G
P
A
S
H
S
C
F
S
R
D
Rhesus Macaque
Macaca mulatta
XP_001084703
580
62690
S571
R
V
S
Q
G
P
A
S
H
S
C
F
S
R
D
Dog
Lupus familis
XP_852542
566
61087
N558
D
R
Q
R
S
R
A
N
G
A
P
A
S
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BPX9
578
64032
S569
R
T
R
Q
D
P
A
S
Q
R
S
S
S
R
V
Rat
Rattus norvegicus
Q924V4
582
64575
S573
R
T
R
Q
D
P
D
S
Q
N
S
T
S
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508474
657
71951
A636
L
S
A
A
A
G
A
A
S
A
A
A
A
V
G
Chicken
Gallus gallus
XP_415099
492
54115
N484
D
H
Q
K
S
K
M
N
D
V
A
A
N
G
R
Frog
Xenopus laevis
Q68F72
569
63068
Q561
I
S
V
K
Y
E
R
Q
Q
S
K
T
Y
R
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783351
614
68101
Q587
M
N
S
H
P
G
S
Q
S
G
P
S
S
L
K
Poplar Tree
Populus trichocarpa
XP_002315835
584
64173
F574
L
N
M
L
V
Y
V
F
C
A
R
K
Y
K
Q
Maize
Zea mays
NP_001146682
587
64502
L576
L
N
L
I
V
Y
V
L
C
A
G
K
Y
K
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LFB8
570
63290
Y562
W
I
A
K
W
Y
T
Y
K
K
T
T
G
H
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.5
88.6
50.5
N.A.
80.7
80.9
N.A.
35.6
43.8
48.1
N.A.
N.A.
N.A.
N.A.
N.A.
39.2
Protein Similarity:
100
89.8
91.3
66.9
N.A.
86.5
86.7
N.A.
50.8
58.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
54.5
P-Site Identity:
100
93.3
86.6
20
N.A.
46.6
40
N.A.
6.6
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
93.3
86.6
40
N.A.
46.6
46.6
N.A.
40
20
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
28
28.4
N.A.
25.8
N.A.
N.A.
Protein Similarity:
47.4
47.3
N.A.
46.3
N.A.
N.A.
P-Site Identity:
6.6
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
20
13.3
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
16
8
8
0
47
8
0
31
16
24
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
16
0
16
0
0
0
0
% C
% Asp:
16
0
0
0
16
0
8
0
8
0
0
0
0
0
24
% D
% Glu:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
24
0
0
0
% F
% Gly:
0
0
0
0
24
16
0
0
8
8
8
0
8
8
8
% G
% His:
0
8
0
8
0
0
0
0
24
0
0
0
0
8
0
% H
% Ile:
8
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
24
0
8
0
0
8
8
8
16
0
16
8
% K
% Leu:
24
0
8
8
0
0
0
8
0
0
0
0
0
8
0
% L
% Met:
8
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
24
0
0
0
0
0
16
0
8
0
0
8
0
0
% N
% Pro:
0
0
0
0
8
39
0
0
0
0
16
0
0
0
0
% P
% Gln:
0
0
16
39
0
0
0
16
24
0
0
0
0
0
8
% Q
% Arg:
39
8
16
8
0
8
8
0
0
8
16
0
0
54
24
% R
% Ser:
0
16
31
0
16
0
8
39
16
31
16
16
54
0
8
% S
% Thr:
0
16
0
0
0
0
8
0
0
0
8
24
0
0
0
% T
% Val:
0
8
8
0
16
0
16
0
0
8
0
0
0
8
16
% V
% Trp:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
24
0
8
0
0
0
0
24
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _