KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC15A3
All Species:
11.52
Human Site:
T121
Identified Species:
21.11
UniProt:
Q8IY34
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY34
NP_057666.1
581
63560
T121
A
S
G
L
L
P
A
T
A
F
P
D
G
R
S
Chimpanzee
Pan troglodytes
XP_508467
527
57583
F76
F
P
D
G
R
S
S
F
C
G
E
M
P
A
S
Rhesus Macaque
Macaca mulatta
XP_001084703
580
62690
T121
A
S
G
L
L
P
A
T
A
F
P
D
G
R
S
Dog
Lupus familis
XP_852542
566
61087
P110
L
L
G
M
L
A
L
P
L
L
A
A
P
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BPX9
578
64032
T121
A
S
G
L
L
L
T
T
I
T
N
D
G
R
R
Rat
Rattus norvegicus
Q924V4
582
64575
T121
A
T
G
L
L
L
T
T
I
T
D
D
G
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508474
657
71951
L169
G
K
R
K
I
S
G
L
D
A
C
S
L
P
Q
Chicken
Gallus gallus
XP_415099
492
54115
T76
T
R
Y
C
A
A
A
T
F
V
G
L
V
L
V
Frog
Xenopus laevis
Q68F72
569
63068
G124
F
P
M
V
S
Y
S
G
T
R
T
A
F
C
G
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783351
614
68101
N136
G
F
A
S
I
K
G
N
H
D
F
M
C
T
L
Poplar Tree
Populus trichocarpa
XP_002315835
584
64173
Y124
I
A
A
F
S
S
I
Y
F
I
G
M
C
A
L
Maize
Zea mays
NP_001146682
587
64502
S123
Y
W
T
I
A
T
F
S
T
V
Y
F
I
G
M
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LFB8
570
63290
V105
W
T
I
A
S
F
V
V
I
Y
I
A
G
M
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.5
88.6
50.5
N.A.
80.7
80.9
N.A.
35.6
43.8
48.1
N.A.
N.A.
N.A.
N.A.
N.A.
39.2
Protein Similarity:
100
89.8
91.3
66.9
N.A.
86.5
86.7
N.A.
50.8
58.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
54.5
P-Site Identity:
100
6.6
100
13.3
N.A.
60
53.3
N.A.
0
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
13.3
100
20
N.A.
60
60
N.A.
6.6
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
28
28.4
N.A.
25.8
N.A.
N.A.
Protein Similarity:
47.4
47.3
N.A.
46.3
N.A.
N.A.
P-Site Identity:
0
0
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
6.6
13.3
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
31
8
16
8
16
16
24
0
16
8
8
24
0
24
0
% A
% Cys:
0
0
0
8
0
0
0
0
8
0
8
0
16
8
0
% C
% Asp:
0
0
8
0
0
0
0
0
8
8
8
31
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% E
% Phe:
16
8
0
8
0
8
8
8
16
16
8
8
8
0
0
% F
% Gly:
16
0
39
8
0
0
16
8
0
8
16
0
39
8
8
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
8
0
8
8
16
0
8
0
24
8
8
0
8
0
0
% I
% Lys:
0
8
0
8
0
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
8
0
31
39
16
8
8
8
8
0
8
8
8
16
% L
% Met:
0
0
8
8
0
0
0
0
0
0
0
24
0
8
8
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% N
% Pro:
0
16
0
0
0
16
0
8
0
0
16
0
16
8
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
8
8
0
8
0
0
0
0
8
0
0
0
31
16
% R
% Ser:
0
24
0
8
24
24
16
8
0
0
0
8
0
0
24
% S
% Thr:
8
16
8
0
0
8
16
39
16
16
8
0
0
8
8
% T
% Val:
0
0
0
8
0
0
8
8
0
16
0
0
8
0
8
% V
% Trp:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
0
8
0
8
0
8
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _