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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC15A3
All Species:
19.7
Human Site:
Y563
Identified Species:
36.11
UniProt:
Q8IY34
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY34
NP_057666.1
581
63560
Y563
F
V
W
I
A
G
R
Y
E
R
A
S
Q
G
P
Chimpanzee
Pan troglodytes
XP_508467
527
57583
Y509
F
V
W
I
A
G
R
Y
E
R
A
S
Q
G
P
Rhesus Macaque
Macaca mulatta
XP_001084703
580
62690
Y562
F
V
W
I
A
G
R
Y
E
R
V
S
Q
G
P
Dog
Lupus familis
XP_852542
566
61087
R549
L
F
L
I
V
S
V
R
Y
D
R
Q
R
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BPX9
578
64032
Y560
F
L
W
I
A
G
R
Y
E
R
T
R
Q
D
P
Rat
Rattus norvegicus
Q924V4
582
64575
Y564
F
L
W
I
A
G
R
Y
E
R
T
R
Q
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508474
657
71951
H627
P
L
P
Q
L
G
R
H
G
L
S
A
A
A
G
Chicken
Gallus gallus
XP_415099
492
54115
K475
L
F
L
I
V
S
V
K
Y
D
H
Q
K
S
K
Frog
Xenopus laevis
Q68F72
569
63068
L552
A
A
T
L
L
L
F
L
I
I
S
V
K
Y
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783351
614
68101
N578
F
F
M
Y
N
R
G
N
V
M
N
S
H
P
G
Poplar Tree
Populus trichocarpa
XP_002315835
584
64173
S565
F
W
L
L
A
G
L
S
V
L
N
M
L
V
Y
Maize
Zea mays
NP_001146682
587
64502
S567
F
L
L
I
A
G
I
S
F
L
N
L
I
V
Y
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LFB8
570
63290
Y553
S
F
L
N
F
L
V
Y
L
W
I
A
K
W
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.5
88.6
50.5
N.A.
80.7
80.9
N.A.
35.6
43.8
48.1
N.A.
N.A.
N.A.
N.A.
N.A.
39.2
Protein Similarity:
100
89.8
91.3
66.9
N.A.
86.5
86.7
N.A.
50.8
58.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
54.5
P-Site Identity:
100
100
93.3
6.6
N.A.
73.3
73.3
N.A.
13.3
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
93.3
13.3
N.A.
80
80
N.A.
40
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
28
28.4
N.A.
25.8
N.A.
N.A.
Protein Similarity:
47.4
47.3
N.A.
46.3
N.A.
N.A.
P-Site Identity:
20
26.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
26.6
33.3
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
54
0
0
0
0
0
16
16
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
16
0
0
0
16
0
% D
% Glu:
0
0
0
0
0
0
0
0
39
0
0
0
0
0
8
% E
% Phe:
62
31
0
0
8
0
8
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
62
8
0
8
0
0
0
0
24
16
% G
% His:
0
0
0
0
0
0
0
8
0
0
8
0
8
0
0
% H
% Ile:
0
0
0
62
0
0
8
0
8
8
8
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
0
0
24
0
8
% K
% Leu:
16
31
39
16
16
16
8
8
8
24
0
8
8
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
8
0
8
0
0
0
% M
% Asn:
0
0
0
8
8
0
0
8
0
0
24
0
0
0
0
% N
% Pro:
8
0
8
0
0
0
0
0
0
0
0
0
0
8
39
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
16
39
0
0
% Q
% Arg:
0
0
0
0
0
8
47
8
0
39
8
16
8
0
8
% R
% Ser:
8
0
0
0
0
16
0
16
0
0
16
31
0
16
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
16
0
0
0
0
% T
% Val:
0
24
0
0
16
0
24
0
16
0
8
8
0
16
0
% V
% Trp:
0
8
39
0
0
0
0
0
0
8
0
0
0
8
0
% W
% Tyr:
0
0
0
8
0
0
0
47
16
0
0
0
0
8
24
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _