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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX37
All Species:
16.36
Human Site:
S145
Identified Species:
32.73
UniProt:
Q8IY37
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY37
NP_116045.2
1157
129545
S145
P
G
Q
E
K
I
S
S
L
S
G
A
H
R
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103101
1146
127695
S144
A
P
G
Q
E
K
I
S
S
L
S
G
A
H
R
Dog
Lupus familis
XP_534640
1149
128641
S145
Q
R
Q
E
K
I
S
S
L
S
G
A
H
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHK9
1001
113864
P112
A
Q
I
S
W
F
A
P
E
D
H
G
Y
G
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508258
1135
128020
E143
H
K
K
R
R
Q
E
E
L
E
A
E
E
S
E
Chicken
Gallus gallus
XP_415104
1141
127222
S146
A
V
P
E
K
I
R
S
I
S
G
A
N
K
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001076473
1152
129559
S146
S
S
S
V
K
I
S
S
L
S
G
A
N
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O46072
1192
134102
A155
A
S
G
L
R
V
N
A
I
K
G
S
K
R
K
Honey Bee
Apis mellifera
XP_001121639
1118
128185
T144
E
K
E
I
I
E
K
T
I
S
N
L
N
V
I
Nematode Worm
Caenorhab. elegans
P34305
1148
129944
T139
T
Q
Q
D
Y
Y
P
T
D
D
E
S
S
S
E
Sea Urchin
Strong. purpuratus
XP_786550
1324
147742
S218
H
E
D
K
N
S
A
S
V
Y
R
T
I
D
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04217
1267
144936
W248
T
P
K
K
K
Y
N
W
R
Q
R
V
E
M
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.4
86.5
N.A.
23.1
N.A.
N.A.
73.1
72.1
N.A.
66.2
N.A.
45.5
48.1
41.4
49.4
Protein Similarity:
100
N.A.
96.1
92
N.A.
42.2
N.A.
N.A.
84
83.4
N.A.
78.8
N.A.
63.3
66.6
57.3
63.9
P-Site Identity:
100
N.A.
6.6
86.6
N.A.
0
N.A.
N.A.
6.6
46.6
N.A.
66.6
N.A.
20
6.6
6.6
13.3
P-Site Similarity:
100
N.A.
26.6
86.6
N.A.
13.3
N.A.
N.A.
26.6
73.3
N.A.
73.3
N.A.
60
33.3
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
0
0
0
0
0
17
9
0
0
9
34
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
9
0
0
0
0
9
17
0
0
0
9
0
% D
% Glu:
9
9
9
25
9
9
9
9
9
9
9
9
17
0
25
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
17
0
0
0
0
0
0
0
42
17
0
9
0
% G
% His:
17
0
0
0
0
0
0
0
0
0
9
0
17
9
0
% H
% Ile:
0
0
9
9
9
34
9
0
25
0
0
0
9
0
9
% I
% Lys:
0
17
17
17
42
9
9
0
0
9
0
0
9
9
42
% K
% Leu:
0
0
0
9
0
0
0
0
34
9
0
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
0
9
0
17
0
0
0
9
0
25
0
0
% N
% Pro:
9
17
9
0
0
0
9
9
0
0
0
0
0
0
0
% P
% Gln:
9
17
25
9
0
9
0
0
0
9
0
0
0
0
0
% Q
% Arg:
0
9
0
9
17
0
9
0
9
0
17
0
0
34
17
% R
% Ser:
9
17
9
9
0
9
25
50
9
42
9
17
9
17
0
% S
% Thr:
17
0
0
0
0
0
0
17
0
0
0
9
0
0
9
% T
% Val:
0
9
0
9
0
9
0
0
9
0
0
9
0
9
0
% V
% Trp:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
17
0
0
0
9
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _