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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TIGD4
All Species:
25.15
Human Site:
S488
Identified Species:
79.05
UniProt:
Q8IY51
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY51
NP_663772.1
512
57454
S488
T
L
K
K
F
L
R
S
Q
D
M
N
D
G
L
Chimpanzee
Pan troglodytes
XP_001153845
512
57504
S488
T
L
K
K
F
L
R
S
Q
D
M
N
D
G
L
Rhesus Macaque
Macaca mulatta
XP_001085140
512
57362
S488
T
L
K
K
F
L
R
S
Q
D
M
N
D
G
L
Dog
Lupus familis
XP_532690
511
57658
S488
T
L
K
N
F
L
R
S
Q
D
M
S
D
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BUZ3
513
57453
S489
T
L
K
R
F
L
R
S
H
D
L
N
D
E
L
Rat
Rattus norvegicus
XP_227318
514
57492
S490
T
L
K
R
F
L
R
S
H
D
M
N
D
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511803
514
58339
S490
T
F
K
R
F
L
R
S
Q
E
M
N
D
G
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784717
513
58187
Q480
E
H
L
R
R
F
V
Q
E
N
A
M
N
H
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
97.6
91.4
N.A.
84.9
84.4
N.A.
78
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
25.7
Protein Similarity:
100
99.6
98.8
94.7
N.A.
90.6
90.4
N.A.
87.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
46
P-Site Identity:
100
100
100
80
N.A.
73.3
80
N.A.
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
75
0
0
88
0
0
% D
% Glu:
13
0
0
0
0
0
0
0
13
13
0
0
0
38
0
% E
% Phe:
0
13
0
0
88
13
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
0
% G
% His:
0
13
0
0
0
0
0
0
25
0
0
0
0
13
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
88
38
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
75
13
0
0
88
0
0
0
0
13
0
0
0
100
% L
% Met:
0
0
0
0
0
0
0
0
0
0
75
13
0
0
0
% M
% Asn:
0
0
0
13
0
0
0
0
0
13
0
75
13
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
13
63
0
0
0
0
0
0
% Q
% Arg:
0
0
0
50
13
0
88
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
88
0
0
0
13
0
0
0
% S
% Thr:
88
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _