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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TIGD4 All Species: 4.24
Human Site: T238 Identified Species: 13.33
UniProt: Q8IY51 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IY51 NP_663772.1 512 57454 T238 L V I G K K R T P H C F K G L
Chimpanzee Pan troglodytes XP_001153845 512 57504 N238 L V I G K K R N P H C F K G L
Rhesus Macaque Macaca mulatta XP_001085140 512 57362 N238 L V I G K K R N P H C F K G L
Dog Lupus familis XP_532690 511 57658 T238 L V I G K N K T P H C F K G I
Cat Felis silvestris
Mouse Mus musculus Q8BUZ3 513 57453 A238 L I I G K N R A P R C F K G I
Rat Rattus norvegicus XP_227318 514 57492 A238 L I I G K N R A P H C F K G V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511803 514 58339 N237 L V I G K N K N P L C F K G I
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784717 513 58187 K230 L A I G E T K K S K S F P K D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 97.6 91.4 N.A. 84.9 84.4 N.A. 78 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 25.7
Protein Similarity: 100 99.6 98.8 94.7 N.A. 90.6 90.4 N.A. 87.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 46
P-Site Identity: 100 93.3 93.3 80 N.A. 66.6 73.3 N.A. 66.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 26.6
P-Site Similarity: 100 93.3 93.3 93.3 N.A. 80 86.6 N.A. 80 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 0 0 0 0 0 25 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 88 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % D
% Glu: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % F
% Gly: 0 0 0 100 0 0 0 0 0 0 0 0 0 88 0 % G
% His: 0 0 0 0 0 0 0 0 0 63 0 0 0 0 0 % H
% Ile: 0 25 100 0 0 0 0 0 0 0 0 0 0 0 38 % I
% Lys: 0 0 0 0 88 38 38 13 0 13 0 0 88 13 0 % K
% Leu: 100 0 0 0 0 0 0 0 0 13 0 0 0 0 38 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 50 0 38 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 88 0 0 0 13 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 63 0 0 13 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 13 0 13 0 0 0 0 % S
% Thr: 0 0 0 0 0 13 0 25 0 0 0 0 0 0 0 % T
% Val: 0 63 0 0 0 0 0 0 0 0 0 0 0 0 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _