KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YAF2
All Species:
11.21
Human Site:
S144
Identified Species:
30.83
UniProt:
Q8IY57
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY57
NP_005739.2
180
19901
S144
P
P
A
S
S
A
A
S
A
D
Q
H
S
Q
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090294
180
19910
S144
P
P
A
S
S
A
A
S
A
D
Q
H
S
Q
S
Dog
Lupus familis
XP_852220
334
36970
S298
P
P
A
S
S
A
A
S
A
D
Q
H
S
Q
S
Cat
Felis silvestris
Mouse
Mus musculus
Q99LW6
179
19636
G144
A
P
A
S
S
A
A
G
D
Q
H
S
Q
G
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514663
171
18884
A136
P
A
S
S
A
A
S
A
D
Q
H
S
Q
S
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SYB3
385
43277
D144
L
D
K
P
Q
A
L
D
T
D
R
R
P
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611705
150
16836
T115
T
A
Q
T
R
E
V
T
V
N
S
V
T
V
F
Honey Bee
Apis mellifera
XP_001120813
226
25317
T184
N
N
V
T
V
V
I
T
E
Y
K
P
K
V
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780545
145
16465
P110
Q
V
V
V
N
D
V
P
V
I
I
T
E
Y
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.4
53.8
N.A.
91.6
N.A.
N.A.
93.3
N.A.
N.A.
32.9
N.A.
45.5
38.9
N.A.
42.7
Protein Similarity:
100
N.A.
100
53.8
N.A.
94.4
N.A.
N.A.
94.4
N.A.
N.A.
39.4
N.A.
54.4
49.5
N.A.
56.1
P-Site Identity:
100
N.A.
100
100
N.A.
46.6
N.A.
N.A.
20
N.A.
N.A.
13.3
N.A.
0
0
N.A.
0
P-Site Similarity:
100
N.A.
100
100
N.A.
46.6
N.A.
N.A.
46.6
N.A.
N.A.
26.6
N.A.
26.6
20
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
23
45
0
12
67
45
12
34
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
0
0
12
0
12
23
45
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
12
0
0
12
0
0
0
12
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
0
0
0
0
0
0
12
0
0
0
0
0
12
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
23
34
0
0
0
% H
% Ile:
0
0
0
0
0
0
12
0
0
12
12
0
0
0
0
% I
% Lys:
0
0
12
0
0
0
0
0
0
0
12
0
12
0
12
% K
% Leu:
12
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
12
0
0
12
0
0
0
0
12
0
0
0
0
0
% N
% Pro:
45
45
0
12
0
0
0
12
0
0
0
12
12
0
0
% P
% Gln:
12
0
12
0
12
0
0
0
0
23
34
0
23
34
0
% Q
% Arg:
0
0
0
0
12
0
0
0
0
0
12
12
0
0
23
% R
% Ser:
0
0
12
56
45
0
12
34
0
0
12
23
34
12
45
% S
% Thr:
12
0
0
23
0
0
0
23
12
0
0
12
12
0
0
% T
% Val:
0
12
23
12
12
12
23
0
23
0
0
12
0
23
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
12
0
0
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _