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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: YAF2 All Species: 9.09
Human Site: S163 Identified Species: 25
UniProt: Q8IY57 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IY57 NP_005739.2 180 19901 S163 D N T E R G M S R S S S P R G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001090294 180 19910 S163 D N T E R G M S R S S S P R G
Dog Lupus familis XP_852220 334 36970 S317 D N T E R G M S R S S S P R G
Cat Felis silvestris
Mouse Mus musculus Q99LW6 179 19636 R163 S T E R G V S R S S S P R G E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514663 171 18884 R155 N T E R G M S R S S S P R G E
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q7SYB3 385 43277 Q163 P D L L Q Q Q Q P Q P Q Q H P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611705 150 16836 R134 K A K P V S S R R E S S E Q S
Honey Bee Apis mellifera XP_001120813 226 25317 A203 Q S G L S S S A S S E N G S Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780545 145 16465 D129 T K V S P D S D D N T S S G D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.4 53.8 N.A. 91.6 N.A. N.A. 93.3 N.A. N.A. 32.9 N.A. 45.5 38.9 N.A. 42.7
Protein Similarity: 100 N.A. 100 53.8 N.A. 94.4 N.A. N.A. 94.4 N.A. N.A. 39.4 N.A. 54.4 49.5 N.A. 56.1
P-Site Identity: 100 N.A. 100 100 N.A. 13.3 N.A. N.A. 13.3 N.A. N.A. 0 N.A. 20 6.6 N.A. 6.6
P-Site Similarity: 100 N.A. 100 100 N.A. 13.3 N.A. N.A. 20 N.A. N.A. 13.3 N.A. 26.6 26.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 0 0 0 0 12 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 34 12 0 0 0 12 0 12 12 0 0 0 0 0 12 % D
% Glu: 0 0 23 34 0 0 0 0 0 12 12 0 12 0 23 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 12 0 23 34 0 0 0 0 0 0 12 34 34 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 12 12 12 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 12 23 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 12 34 0 0 0 0 0 0 0 0 % M
% Asn: 12 34 0 0 0 0 0 0 0 12 0 12 0 0 0 % N
% Pro: 12 0 0 12 12 0 0 0 12 0 12 23 34 0 12 % P
% Gln: 12 0 0 0 12 12 12 12 0 12 0 12 12 12 12 % Q
% Arg: 0 0 0 23 34 0 0 34 45 0 0 0 23 34 0 % R
% Ser: 12 12 0 12 12 23 56 34 34 67 67 56 12 12 12 % S
% Thr: 12 23 34 0 0 0 0 0 0 0 12 0 0 0 0 % T
% Val: 0 0 12 0 12 12 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _