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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YAF2
All Species:
14.55
Human Site:
S166
Identified Species:
40
UniProt:
Q8IY57
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY57
NP_005739.2
180
19901
S166
E
R
G
M
S
R
S
S
S
P
R
G
E
A
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090294
180
19910
S166
E
R
G
M
S
R
S
S
S
P
R
G
E
A
S
Dog
Lupus familis
XP_852220
334
36970
S320
E
R
G
M
S
R
S
S
S
P
R
G
E
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q99LW6
179
19636
S166
R
G
V
S
R
S
S
S
P
R
G
E
A
S
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514663
171
18884
S158
R
G
M
S
R
S
S
S
P
R
G
E
A
S
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SYB3
385
43277
P166
L
Q
Q
Q
Q
P
Q
P
Q
Q
H
P
Q
Q
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611705
150
16836
S137
P
V
S
S
R
R
E
S
S
E
Q
S
F
S
E
Honey Bee
Apis mellifera
XP_001120813
226
25317
E206
L
S
S
S
A
S
S
E
N
G
S
Q
H
D
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780545
145
16465
T132
S
P
D
S
D
D
N
T
S
S
G
D
Q
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.4
53.8
N.A.
91.6
N.A.
N.A.
93.3
N.A.
N.A.
32.9
N.A.
45.5
38.9
N.A.
42.7
Protein Similarity:
100
N.A.
100
53.8
N.A.
94.4
N.A.
N.A.
94.4
N.A.
N.A.
39.4
N.A.
54.4
49.5
N.A.
56.1
P-Site Identity:
100
N.A.
100
100
N.A.
20
N.A.
N.A.
20
N.A.
N.A.
0
N.A.
20
13.3
N.A.
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
26.6
N.A.
N.A.
26.6
N.A.
N.A.
13.3
N.A.
33.3
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
0
0
0
0
0
0
23
34
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
0
12
12
0
0
0
0
0
12
0
12
0
% D
% Glu:
34
0
0
0
0
0
12
12
0
12
0
23
34
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% F
% Gly:
0
23
34
0
0
0
0
0
0
12
34
34
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
12
0
12
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
23
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
12
34
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
12
0
12
0
0
0
0
0
0
% N
% Pro:
12
12
0
0
0
12
0
12
23
34
0
12
0
0
12
% P
% Gln:
0
12
12
12
12
0
12
0
12
12
12
12
23
12
0
% Q
% Arg:
23
34
0
0
34
45
0
0
0
23
34
0
0
0
0
% R
% Ser:
12
12
23
56
34
34
67
67
56
12
12
12
0
34
67
% S
% Thr:
0
0
0
0
0
0
0
12
0
0
0
0
0
12
12
% T
% Val:
0
12
12
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _