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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: YAF2 All Species: 9.09
Human Site: T134 Identified Species: 25
UniProt: Q8IY57 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IY57 NP_005739.2 180 19901 T134 I T D F K E K T K S P P A S S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001090294 180 19910 T134 I T D F K E K T K S P P A S S
Dog Lupus familis XP_852220 334 36970 T288 I T D F K E K T K S P P A S S
Cat Felis silvestris
Mouse Mus musculus Q99LW6 179 19636 A134 I T D F K E K A K S A P A S S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514663 171 18884 K126 T D F K E K T K S P P A S S A
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q7SYB3 385 43277 E134 S L K E R R Q E R V L D K P Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611705 150 16836 D105 P A R L K N V D R S T A Q T R
Honey Bee Apis mellifera XP_001120813 226 25317 V174 S T A Q T N E V T V N N V T V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780545 145 16465 I100 N V D R S T A I S T Q V V V N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.4 53.8 N.A. 91.6 N.A. N.A. 93.3 N.A. N.A. 32.9 N.A. 45.5 38.9 N.A. 42.7
Protein Similarity: 100 N.A. 100 53.8 N.A. 94.4 N.A. N.A. 94.4 N.A. N.A. 39.4 N.A. 54.4 49.5 N.A. 56.1
P-Site Identity: 100 N.A. 100 100 N.A. 86.6 N.A. N.A. 13.3 N.A. N.A. 0 N.A. 13.3 6.6 N.A. 6.6
P-Site Similarity: 100 N.A. 100 100 N.A. 86.6 N.A. N.A. 40 N.A. N.A. 20 N.A. 26.6 20 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 12 0 0 0 12 12 0 0 12 23 45 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 12 56 0 0 0 0 12 0 0 0 12 0 0 0 % D
% Glu: 0 0 0 12 12 45 12 12 0 0 0 0 0 0 0 % E
% Phe: 0 0 12 45 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 45 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % I
% Lys: 0 0 12 12 56 12 45 12 45 0 0 0 12 0 0 % K
% Leu: 0 12 0 12 0 0 0 0 0 0 12 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 12 0 0 0 0 23 0 0 0 0 12 12 0 0 12 % N
% Pro: 12 0 0 0 0 0 0 0 0 12 45 45 0 12 0 % P
% Gln: 0 0 0 12 0 0 12 0 0 0 12 0 12 0 12 % Q
% Arg: 0 0 12 12 12 12 0 0 23 0 0 0 0 0 12 % R
% Ser: 23 0 0 0 12 0 0 0 23 56 0 0 12 56 45 % S
% Thr: 12 56 0 0 12 12 12 34 12 12 12 0 0 23 0 % T
% Val: 0 12 0 0 0 0 12 12 0 23 0 12 23 12 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _