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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: YAF2 All Species: 13.64
Human Site: Y22 Identified Species: 37.5
UniProt: Q8IY57 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IY57 NP_005739.2 180 19901 Y22 K P S S D E G Y W D C S V C T
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001090294 180 19910 Y22 K P S S D E G Y W D C S V C T
Dog Lupus familis XP_852220 334 36970 Y176 K P S S D E G Y W D C S V C T
Cat Felis silvestris
Mouse Mus musculus Q99LW6 179 19636 Y22 K P A S D E G Y W D C S V C T
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514663 171 18884 W14 P A S D E G Y W D C S V C T F
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q7SYB3 385 43277 F22 K P S A D N G F W D C S V C T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611705 150 16836
Honey Bee Apis mellifera XP_001120813 226 25317 G62 F N E A E S T G K R Q A K V L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780545 145 16465
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.4 53.8 N.A. 91.6 N.A. N.A. 93.3 N.A. N.A. 32.9 N.A. 45.5 38.9 N.A. 42.7
Protein Similarity: 100 N.A. 100 53.8 N.A. 94.4 N.A. N.A. 94.4 N.A. N.A. 39.4 N.A. 54.4 49.5 N.A. 56.1
P-Site Identity: 100 N.A. 100 100 N.A. 93.3 N.A. N.A. 6.6 N.A. N.A. 80 N.A. 0 0 N.A. 0
P-Site Similarity: 100 N.A. 100 100 N.A. 100 N.A. N.A. 20 N.A. N.A. 93.3 N.A. 0 20 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 12 23 0 0 0 0 0 0 0 12 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 12 56 0 12 56 0 % C
% Asp: 0 0 0 12 56 0 0 0 12 56 0 0 0 0 0 % D
% Glu: 0 0 12 0 23 45 0 0 0 0 0 0 0 0 0 % E
% Phe: 12 0 0 0 0 0 0 12 0 0 0 0 0 0 12 % F
% Gly: 0 0 0 0 0 12 56 12 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 56 0 0 0 0 0 0 0 12 0 0 0 12 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 12 0 0 0 12 0 0 0 0 0 0 0 0 0 % N
% Pro: 12 56 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % R
% Ser: 0 0 56 45 0 12 0 0 0 0 12 56 0 0 0 % S
% Thr: 0 0 0 0 0 0 12 0 0 0 0 0 0 12 56 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 12 56 12 0 % V
% Trp: 0 0 0 0 0 0 0 12 56 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 12 45 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _