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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC135
All Species:
9.09
Human Site:
T638
Identified Species:
20
UniProt:
Q8IY82
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY82
NP_115645.4
874
103497
T638
K
R
E
F
L
R
R
T
E
V
D
S
K
G
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001100628
830
97575
C622
R
I
Q
L
R
Y
H
C
R
D
D
H
I
T
A
Dog
Lupus familis
XP_544386
903
106348
T667
K
R
E
F
L
R
R
T
E
V
D
S
K
G
N
Cat
Felis silvestris
Mouse
Mus musculus
Q6V3W6
876
103192
M640
K
R
E
F
L
R
R
M
E
V
D
S
K
G
N
Rat
Rattus norvegicus
NP_001099639
874
102795
T638
K
R
E
F
L
R
R
T
E
V
D
S
K
G
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508368
860
101476
A624
K
R
E
F
I
K
R
A
E
V
D
N
K
G
N
Chicken
Gallus gallus
XP_425101
868
101713
P633
S
K
K
D
F
F
K
P
T
E
S
Y
R
K
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_683491
721
83926
V513
N
Q
R
P
I
K
S
V
E
E
R
F
H
R
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036757
897
105223
P653
T
V
V
E
F
T
K
P
P
R
P
D
Y
G
K
Honey Bee
Apis mellifera
XP_396764
568
66652
R360
E
K
F
N
R
D
E
R
I
K
A
S
K
N
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795345
497
57872
H289
E
L
Y
G
L
R
I
H
C
W
V
L
V
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
89.1
81.4
N.A.
82.7
83.9
N.A.
68.6
56.1
N.A.
36.9
N.A.
29.2
24.1
N.A.
31
Protein Similarity:
100
N.A.
91.3
88.5
N.A.
90.1
90.9
N.A.
83.7
70.5
N.A.
53.8
N.A.
49.5
38.4
N.A.
41.4
P-Site Identity:
100
N.A.
6.6
100
N.A.
93.3
100
N.A.
73.3
0
N.A.
6.6
N.A.
6.6
13.3
N.A.
13.3
P-Site Similarity:
100
N.A.
20
100
N.A.
93.3
100
N.A.
93.3
26.6
N.A.
33.3
N.A.
13.3
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
10
0
0
0
10
55
10
0
0
10
% D
% Glu:
19
0
46
10
0
0
10
0
55
19
0
0
0
0
0
% E
% Phe:
0
0
10
46
19
10
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
0
0
0
0
0
55
0
% G
% His:
0
0
0
0
0
0
10
10
0
0
0
10
10
0
0
% H
% Ile:
0
10
0
0
19
0
10
0
10
0
0
0
10
0
10
% I
% Lys:
46
19
10
0
0
19
19
0
0
10
0
0
55
10
10
% K
% Leu:
0
10
0
10
46
0
0
0
0
0
0
10
0
10
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
10
0
0
0
0
0
0
0
10
0
10
46
% N
% Pro:
0
0
0
10
0
0
0
19
10
0
10
0
0
0
0
% P
% Gln:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
10
46
10
0
19
46
46
10
10
10
10
0
10
10
0
% R
% Ser:
10
0
0
0
0
0
10
0
0
0
10
46
0
0
10
% S
% Thr:
10
0
0
0
0
10
0
28
10
0
0
0
0
10
0
% T
% Val:
0
10
10
0
0
0
0
10
0
46
10
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
10
0
0
0
0
0
10
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _