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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM192
All Species:
19.7
Human Site:
S221
Identified Species:
43.33
UniProt:
Q8IY95
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IY95
NP_001093859.1
271
30922
S221
A
Y
P
S
N
I
T
S
E
T
G
F
R
T
I
Chimpanzee
Pan troglodytes
XP_526719
408
46138
S358
A
Y
P
S
N
I
T
S
E
T
G
F
R
T
I
Rhesus Macaque
Macaca mulatta
XP_001096943
322
36588
S272
A
Y
P
S
N
I
T
S
E
T
G
F
R
T
I
Dog
Lupus familis
XP_532712
307
34643
S258
A
Y
P
S
N
I
T
S
E
T
G
F
R
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXT7
266
30317
S217
E
K
I
Y
A
Y
P
S
N
T
A
S
E
T
G
Rat
Rattus norvegicus
Q5U1Y0
266
30234
P216
E
E
K
C
Y
A
Y
P
S
N
I
A
S
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509512
313
35600
S263
A
Y
P
S
A
I
T
S
E
T
G
F
R
T
S
Chicken
Gallus gallus
XP_420389
271
30825
P221
E
E
K
M
Y
A
Y
P
S
H
I
T
S
E
V
Frog
Xenopus laevis
Q66KF2
261
29612
A211
I
E
E
E
K
I
N
A
Y
E
G
H
V
N
P
Zebra Danio
Brachydanio rerio
Q6NYE7
271
30190
S222
E
R
S
Y
G
C
S
S
D
A
H
T
E
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001123128
270
32019
A219
S
F
T
Q
D
T
Y
A
G
S
N
E
V
G
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
66.1
81.9
70
N.A.
77.8
80.4
N.A.
61.9
67.5
50.9
40.2
N.A.
N.A.
29.1
N.A.
N.A.
Protein Similarity:
100
66.4
82.9
77.1
N.A.
85.9
87.8
N.A.
72.5
80
67.1
61.6
N.A.
N.A.
47.2
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
20
0
N.A.
86.6
0
13.3
13.3
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
20
0
N.A.
86.6
6.6
20
26.6
N.A.
N.A.
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
46
0
0
0
19
19
0
19
0
10
10
10
0
0
0
% A
% Cys:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
37
28
10
10
0
0
0
0
46
10
0
10
19
19
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
46
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
10
0
55
0
0
10
19
% G
% His:
0
0
0
0
0
0
0
0
0
10
10
10
0
0
0
% H
% Ile:
10
0
10
0
0
55
0
0
0
0
19
0
0
0
28
% I
% Lys:
0
10
19
0
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
37
0
10
0
10
10
10
0
0
10
0
% N
% Pro:
0
0
46
0
0
0
10
19
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
0
0
0
0
0
46
0
0
% R
% Ser:
10
0
10
46
0
0
10
64
19
10
0
10
19
0
10
% S
% Thr:
0
0
10
0
0
10
46
0
0
55
0
19
0
64
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
19
0
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
46
0
19
19
10
28
0
10
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _