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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM192 All Species: 14.55
Human Site: T260 Identified Species: 32
UniProt: Q8IY95 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IY95 NP_001093859.1 271 30922 T260 S K R L L A L T S S D L G C Q
Chimpanzee Pan troglodytes XP_526719 408 46138 T397 S K R L L A L T S S D L G C Q
Rhesus Macaque Macaca mulatta XP_001096943 322 36588 T311 S K R L L A L T S S D L D G Q
Dog Lupus familis XP_532712 307 34643 T297 S K R L L T F T S S G D S P P
Cat Felis silvestris
Mouse Mus musculus Q9CXT7 266 30317 L256 N A L L S K R L L E L A T Q P
Rat Rattus norvegicus Q5U1Y0 266 30234 R255 H N A L L S K R L L E L A T Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509512 313 35600 T302 S K R L L T F T S P D S V T R
Chicken Gallus gallus XP_420389 271 30825 R260 H N A L L S K R L L A L T S Q
Frog Xenopus laevis Q66KF2 261 29612 S250 K H H N A L L S K Q L L A L T
Zebra Danio Brachydanio rerio Q6NYE7 271 30190 I261 N S V L S R R I L T L T G Q Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001123128 270 32019 M258 N V K L S H R M M L L A A Q R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 66.1 81.9 70 N.A. 77.8 80.4 N.A. 61.9 67.5 50.9 40.2 N.A. N.A. 29.1 N.A. N.A.
Protein Similarity: 100 66.4 82.9 77.1 N.A. 85.9 87.8 N.A. 72.5 80 67.1 61.6 N.A. N.A. 47.2 N.A. N.A.
P-Site Identity: 100 100 86.6 53.3 N.A. 6.6 26.6 N.A. 53.3 26.6 13.3 20 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 100 100 86.6 53.3 N.A. 13.3 40 N.A. 60 33.3 20 33.3 N.A. N.A. 26.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 19 0 10 28 0 0 0 0 10 19 28 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 19 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 37 10 10 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 10 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 19 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 10 0 28 10 0 % G
% His: 19 10 10 0 0 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % I
% Lys: 10 46 10 0 0 10 19 0 10 0 0 0 0 0 0 % K
% Leu: 0 0 10 91 64 10 37 10 37 28 37 55 0 10 0 % L
% Met: 0 0 0 0 0 0 0 10 10 0 0 0 0 0 0 % M
% Asn: 28 19 0 10 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 19 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 0 0 28 55 % Q
% Arg: 0 0 46 0 0 10 28 19 0 0 0 0 0 0 19 % R
% Ser: 46 10 0 0 28 19 0 10 46 37 0 10 10 10 0 % S
% Thr: 0 0 0 0 0 19 0 46 0 10 0 10 19 19 10 % T
% Val: 0 10 10 0 0 0 0 0 0 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _