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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MKX
All Species:
6.67
Human Site:
T281
Identified Species:
18.33
UniProt:
Q8IYA7
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYA7
NP_775847.2
352
39331
T281
N
F
V
Y
R
T
D
T
L
E
N
G
S
N
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Q8MID6
249
27534
P180
Q
M
S
G
E
K
I
P
E
P
G
S
A
P
S
Dog
Lupus familis
XP_544207
446
49380
A375
N
F
V
Y
R
T
D
A
L
E
N
G
S
N
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BIA3
353
39383
T282
T
F
V
Y
R
T
D
T
P
D
I
G
S
T
K
Rat
Rattus norvegicus
XP_001063892
356
39517
T281
T
F
V
Y
R
T
D
T
P
D
I
G
S
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507016
397
43976
M326
N
F
V
Y
R
T
E
M
L
D
N
G
P
N
K
Chicken
Gallus gallus
Q9YGS0
485
52755
P352
Q
P
L
L
E
A
K
P
R
I
W
S
L
A
H
Frog
Xenopus laevis
Q6DCQ1
455
49451
L321
T
P
A
S
K
P
K
L
W
S
L
A
E
I
A
Zebra Danio
Brachydanio rerio
NP_001092203
349
39185
E277
I
Y
R
T
E
T
V
E
H
G
S
N
K
C
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
20.1
75.1
N.A.
88.9
87.3
N.A.
77
20
25.2
70.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
40
76.4
N.A.
93.4
92.1
N.A.
79.8
34.2
40.8
81.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
0
93.3
N.A.
66.6
66.6
N.A.
73.3
0
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
6.6
93.3
N.A.
73.3
73.3
N.A.
86.6
6.6
6.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
12
0
12
0
0
0
12
12
12
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% C
% Asp:
0
0
0
0
0
0
45
0
0
34
0
0
0
0
12
% D
% Glu:
0
0
0
0
34
0
12
12
12
23
0
0
12
0
0
% E
% Phe:
0
56
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
12
0
0
0
0
0
12
12
56
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
12
% H
% Ile:
12
0
0
0
0
0
12
0
0
12
23
0
0
12
0
% I
% Lys:
0
0
0
0
12
12
23
0
0
0
0
0
12
0
56
% K
% Leu:
0
0
12
12
0
0
0
12
34
0
12
0
12
0
0
% L
% Met:
0
12
0
0
0
0
0
12
0
0
0
0
0
0
0
% M
% Asn:
34
0
0
0
0
0
0
0
0
0
34
12
0
34
0
% N
% Pro:
0
23
0
0
0
12
0
23
23
12
0
0
12
12
0
% P
% Gln:
23
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
12
0
56
0
0
0
12
0
0
0
0
0
0
% R
% Ser:
0
0
12
12
0
0
0
0
0
12
12
23
45
0
12
% S
% Thr:
34
0
0
12
0
67
0
34
0
0
0
0
0
23
0
% T
% Val:
0
0
56
0
0
0
12
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
12
0
12
0
0
0
0
% W
% Tyr:
0
12
0
56
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _