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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PEX5L
All Species:
21.52
Human Site:
S452
Identified Species:
52.59
UniProt:
Q8IYB4
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYB4
NP_057643.1
626
69697
S452
S
K
S
P
V
D
S
S
V
L
E
G
V
K
E
Chimpanzee
Pan troglodytes
XP_001168616
626
69649
S452
S
K
S
P
V
D
S
S
V
L
E
G
V
K
E
Rhesus Macaque
Macaca mulatta
XP_001107641
626
69695
S452
S
K
S
P
V
D
S
S
V
L
E
G
V
K
E
Dog
Lupus familis
XP_545212
650
72297
S476
S
K
S
P
V
D
S
S
V
L
E
G
V
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8C437
567
63116
Y402
L
E
G
V
K
E
L
Y
L
E
A
A
H
Q
N
Rat
Rattus norvegicus
Q925N3
602
66853
S428
S
K
S
P
V
D
S
S
V
L
E
G
V
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506235
285
31765
P133
Q
N
G
E
M
I
D
P
D
L
Q
T
G
L
G
Chicken
Gallus gallus
Q5ZMQ9
645
71772
S472
L
G
S
L
L
S
D
S
L
F
V
E
V
K
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_685057
656
73473
P483
Y
P
C
P
V
S
C
P
L
L
P
E
V
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35056
612
69306
D436
E
K
G
F
T
H
I
D
M
N
A
H
I
T
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.5
94.1
N.A.
87.6
92.9
N.A.
42.1
39.8
N.A.
61.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
99.8
94.7
N.A.
88.8
94.2
N.A.
44.4
55.9
N.A.
75.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
0
93.3
N.A.
6.6
33.3
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
26.6
100
N.A.
20
46.6
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
20
10
0
0
0
% A
% Cys:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
50
20
10
10
0
0
0
0
0
20
% D
% Glu:
10
10
0
10
0
10
0
0
0
10
50
20
0
0
50
% E
% Phe:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
10
30
0
0
0
0
0
0
0
0
50
10
0
10
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
10
10
0
0
% H
% Ile:
0
0
0
0
0
10
10
0
0
0
0
0
10
0
0
% I
% Lys:
0
60
0
0
10
0
0
0
0
0
0
0
0
70
10
% K
% Leu:
20
0
0
10
10
0
10
0
30
70
0
0
0
10
0
% L
% Met:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
10
% N
% Pro:
0
10
0
60
0
0
0
20
0
0
10
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
50
0
60
0
0
20
50
60
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
10
0
0
0
0
0
0
10
0
10
0
% T
% Val:
0
0
0
10
60
0
0
0
50
0
10
0
70
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _