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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DIS3L2
All Species:
24.85
Human Site:
S701
Identified Species:
39.05
UniProt:
Q8IYB7
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYB7
NP_689596.4
885
99210
S701
P
L
Y
T
H
F
T
S
P
I
R
R
F
A
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001114025
580
64957
F404
K
P
L
A
D
G
N
F
E
V
G
V
H
I
A
Dog
Lupus familis
XP_852722
879
98718
S699
P
L
Y
T
H
F
T
S
P
I
R
R
F
A
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8CI75
870
97756
L689
E
Q
F
R
H
Y
A
L
N
V
P
L
Y
T
H
Rat
Rattus norvegicus
Q5U2P0
1054
120741
S797
D
K
Y
T
H
F
T
S
P
I
R
R
Y
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422741
859
96810
F681
V
L
K
D
E
T
L
F
R
H
Y
A
L
N
V
Frog
Xenopus laevis
Q6GN11
1040
119148
S789
E
K
Y
T
H
F
T
S
P
I
R
R
Y
A
D
Zebra Danio
Brachydanio rerio
A2RV18
1057
120333
S789
A
R
Y
T
H
F
T
S
P
I
R
R
Y
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728490
1044
118207
F865
P
M
A
R
A
T
Y
F
C
S
E
G
K
S
E
Honey Bee
Apis mellifera
XP_624734
786
91013
L609
T
V
T
A
E
E
E
L
R
H
Y
A
L
N
V
Nematode Worm
Caenorhab. elegans
Q09568
817
93710
S636
D
H
Y
T
H
F
T
S
P
I
R
R
Y
P
D
Sea Urchin
Strong. purpuratus
XP_001188256
807
90270
L612
E
E
Q
A
K
C
L
L
K
V
L
T
V
L
Y
Poplar Tree
Populus trichocarpa
XP_002302251
860
96450
N682
K
D
D
P
E
L
F
N
I
L
I
N
Y
A
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_177891
1055
116824
S805
P
L
Y
T
H
F
T
S
P
L
R
R
Y
P
D
Baker's Yeast
Sacchar. cerevisiae
Q08162
1001
113688
Y824
Q
Y
F
Y
S
G
A
Y
S
Y
P
D
F
R
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
63.9
89.4
N.A.
85.9
26
N.A.
N.A.
70.4
25.5
25.5
N.A.
29.2
30.3
38.8
43
Protein Similarity:
100
N.A.
64.5
94.1
N.A.
91.5
43.3
N.A.
N.A.
82.3
43.2
42.1
N.A.
46
49.9
58.8
57.8
P-Site Identity:
100
N.A.
0
100
N.A.
6.6
73.3
N.A.
N.A.
6.6
80
80
N.A.
6.6
0
73.3
0
P-Site Similarity:
100
N.A.
6.6
100
N.A.
33.3
86.6
N.A.
N.A.
6.6
86.6
86.6
N.A.
26.6
6.6
80
6.6
Percent
Protein Identity:
33.9
N.A.
N.A.
30.2
28.3
N.A.
Protein Similarity:
49.9
N.A.
N.A.
46
44.7
N.A.
P-Site Identity:
6.6
N.A.
N.A.
80
6.6
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
93.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
20
7
0
14
0
0
0
0
14
0
34
7
% A
% Cys:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
0
% C
% Asp:
14
7
7
7
7
0
0
0
0
0
0
7
0
0
47
% D
% Glu:
20
7
0
0
20
7
7
0
7
0
7
0
0
0
7
% E
% Phe:
0
0
14
0
0
47
7
20
0
0
0
0
20
0
0
% F
% Gly:
0
0
0
0
0
14
0
0
0
0
7
7
0
0
0
% G
% His:
0
7
0
0
54
0
0
0
0
14
0
0
7
0
14
% H
% Ile:
0
0
0
0
0
0
0
0
7
40
7
0
0
7
0
% I
% Lys:
14
14
7
0
7
0
0
0
7
0
0
0
7
0
0
% K
% Leu:
0
27
7
0
0
7
14
20
0
14
7
7
14
7
0
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
7
7
7
0
0
7
0
14
0
% N
% Pro:
27
7
0
7
0
0
0
0
47
0
14
0
0
14
0
% P
% Gln:
7
7
7
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
7
0
14
0
0
0
0
14
0
47
47
0
7
0
% R
% Ser:
0
0
0
0
7
0
0
47
7
7
0
0
0
14
7
% S
% Thr:
7
0
7
47
0
14
47
0
0
0
0
7
0
7
0
% T
% Val:
7
7
0
0
0
0
0
0
0
20
0
7
7
0
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
47
7
0
7
7
7
0
7
14
0
47
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _