KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DIS3L2
All Species:
2.45
Human Site:
S882
Identified Species:
3.85
UniProt:
Q8IYB7
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYB7
NP_689596.4
885
99210
S882
S
D
G
E
P
E
D
S
S
T
S
_
_
_
_
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001114025
580
64957
Dog
Lupus familis
XP_852722
879
98718
Cat
Felis silvestris
Mouse
Mus musculus
Q8CI75
870
97756
A863
K
R
P
G
L
E
K
A
S
D
E
E
P
E
D
Rat
Rattus norvegicus
Q5U2P0
1054
120741
T1035
T
K
G
R
S
L
Y
T
L
L
E
E
I
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422741
859
96810
S856
S
A
L
L
K
R
P
S
A
Q
K
_
_
_
_
Frog
Xenopus laevis
Q6GN11
1040
119148
G1019
Q
E
Y
R
Q
T
Q
G
Q
S
L
Y
T
M
L
Zebra Danio
Brachydanio rerio
A2RV18
1057
120333
C1053
T
N
S
E
E
Q
T
C
T
V
S
S
_
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728490
1044
118207
Honey Bee
Apis mellifera
XP_624734
786
91013
Nematode Worm
Caenorhab. elegans
Q09568
817
93710
Sea Urchin
Strong. purpuratus
XP_001188256
807
90270
L797
F
S
Q
V
T
V
E
L
T
A
D
R
M
P
G
Poplar Tree
Populus trichocarpa
XP_002302251
860
96450
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_177891
1055
116824
P1030
I
Q
L
F
S
T
I
P
V
V
L
H
A
V
G
Baker's Yeast
Sacchar. cerevisiae
Q08162
1001
113688
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
63.9
89.4
N.A.
85.9
26
N.A.
N.A.
70.4
25.5
25.5
N.A.
29.2
30.3
38.8
43
Protein Similarity:
100
N.A.
64.5
94.1
N.A.
91.5
43.3
N.A.
N.A.
82.3
43.2
42.1
N.A.
46
49.9
58.8
57.8
P-Site Identity:
100
N.A.
0
0
N.A.
13.3
6.6
N.A.
N.A.
18.1
0
16.6
N.A.
0
0
0
0
P-Site Similarity:
100
N.A.
0
0
N.A.
20
26.6
N.A.
N.A.
27.2
20
50
N.A.
0
0
0
20
Percent
Protein Identity:
33.9
N.A.
N.A.
30.2
28.3
N.A.
Protein Similarity:
49.9
N.A.
N.A.
46
44.7
N.A.
P-Site Identity:
0
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
0
N.A.
N.A.
6.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
0
7
7
7
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
0
7
0
0
7
7
0
0
0
14
% D
% Glu:
0
7
0
14
7
14
7
0
0
0
14
14
0
7
0
% E
% Phe:
7
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
14
7
0
0
0
7
0
0
0
0
0
0
14
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
7
0
0
0
0
0
7
0
0
0
0
0
7
0
0
% I
% Lys:
7
7
0
0
7
0
7
0
0
0
7
0
0
0
0
% K
% Leu:
0
0
14
7
7
7
0
7
7
7
14
0
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
7
0
% M
% Asn:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
7
0
7
0
7
7
0
0
0
0
7
7
0
% P
% Gln:
7
7
7
0
7
7
7
0
7
7
0
0
0
0
0
% Q
% Arg:
0
7
0
14
0
7
0
0
0
0
0
7
0
7
0
% R
% Ser:
14
7
7
0
14
0
0
14
14
7
14
7
0
0
0
% S
% Thr:
14
0
0
0
7
14
7
7
14
7
0
0
7
0
0
% T
% Val:
0
0
0
7
0
7
0
0
7
14
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
7
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
14
20
20
20
% _