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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DIS3L2
All Species:
8.48
Human Site:
T15
Identified Species:
13.33
UniProt:
Q8IYB7
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYB7
NP_689596.4
885
99210
T15
M
N
L
R
P
L
G
T
P
R
G
V
S
A
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001114025
580
64957
Dog
Lupus familis
XP_852722
879
98718
S18
L
G
T
P
R
G
V
S
S
V
A
G
P
H
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8CI75
870
97756
T15
L
N
L
R
S
P
G
T
P
R
G
V
S
S
V
Rat
Rattus norvegicus
Q5U2P0
1054
120741
E24
R
T
L
R
I
V
R
E
H
Y
L
R
P
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422741
859
96810
T15
I
N
P
R
Q
L
G
T
P
R
G
G
S
Y
A
Frog
Xenopus laevis
Q6GN11
1040
119148
V30
E
H
Y
L
R
E
D
V
R
C
G
S
A
L
C
Zebra Danio
Brachydanio rerio
A2RV18
1057
120333
Y97
H
T
R
G
R
R
H
Y
N
R
L
R
S
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728490
1044
118207
E15
A
H
S
Q
V
M
S
E
T
S
S
V
N
V
D
Honey Bee
Apis mellifera
XP_624734
786
91013
Q15
S
N
F
V
T
Q
N
Q
F
T
F
A
E
K
F
Nematode Worm
Caenorhab. elegans
Q09568
817
93710
K17
T
K
A
K
P
Y
V
K
P
Q
N
A
N
N
L
Sea Urchin
Strong. purpuratus
XP_001188256
807
90270
N15
I
N
G
V
H
A
R
N
R
A
L
Q
G
D
V
Poplar Tree
Populus trichocarpa
XP_002302251
860
96450
G27
L
V
L
S
D
L
D
G
S
M
L
A
K
S
C
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_177891
1055
116824
Q113
S
S
P
E
V
S
K
Q
L
L
S
K
S
C
P
Baker's Yeast
Sacchar. cerevisiae
Q08162
1001
113688
L161
E
H
T
F
V
E
R
L
P
N
E
T
I
N
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
63.9
89.4
N.A.
85.9
26
N.A.
N.A.
70.4
25.5
25.5
N.A.
29.2
30.3
38.8
43
Protein Similarity:
100
N.A.
64.5
94.1
N.A.
91.5
43.3
N.A.
N.A.
82.3
43.2
42.1
N.A.
46
49.9
58.8
57.8
P-Site Identity:
100
N.A.
0
0
N.A.
73.3
20
N.A.
N.A.
60
6.6
13.3
N.A.
6.6
6.6
13.3
13.3
P-Site Similarity:
100
N.A.
0
13.3
N.A.
86.6
33.3
N.A.
N.A.
66.6
20
20
N.A.
33.3
6.6
40
20
Percent
Protein Identity:
33.9
N.A.
N.A.
30.2
28.3
N.A.
Protein Similarity:
49.9
N.A.
N.A.
46
44.7
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
0
7
0
0
0
7
7
20
7
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
7
14
% C
% Asp:
0
0
0
0
7
0
14
0
0
0
0
0
0
7
14
% D
% Glu:
14
0
0
7
0
14
0
14
0
0
7
0
7
0
0
% E
% Phe:
0
0
7
7
0
0
0
0
7
0
7
0
0
0
7
% F
% Gly:
0
7
7
7
0
7
20
7
0
0
27
14
7
0
7
% G
% His:
7
20
0
0
7
0
7
0
7
0
0
0
0
7
0
% H
% Ile:
14
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% I
% Lys:
0
7
0
7
0
0
7
7
0
0
0
7
7
7
0
% K
% Leu:
20
0
27
7
0
20
0
7
7
7
27
0
0
14
14
% L
% Met:
7
0
0
0
0
7
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
34
0
0
0
0
7
7
7
7
7
0
14
14
0
% N
% Pro:
0
0
14
7
14
7
0
0
34
0
0
0
14
0
7
% P
% Gln:
0
0
0
7
7
7
0
14
0
7
0
7
0
0
0
% Q
% Arg:
7
0
7
27
20
7
20
0
14
27
0
14
0
0
0
% R
% Ser:
14
7
7
7
7
7
7
7
14
7
14
7
34
20
0
% S
% Thr:
7
14
14
0
7
0
0
20
7
7
0
7
0
0
0
% T
% Val:
0
7
0
14
20
7
14
7
0
7
0
20
0
7
27
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
7
0
7
0
7
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _