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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SUPV3L1 All Species: 40.3
Human Site: S476 Identified Species: 63.33
UniProt: Q8IYB8 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IYB8 NP_003162.2 786 87991 S476 G R A G R F S S R F K E G E V
Chimpanzee Pan troglodytes XP_521497 786 87916 S476 G R A G R F S S R F K E G E V
Rhesus Macaque Macaca mulatta XP_001110593 787 88079 S477 G R A G R F S S Q F K E G E V
Dog Lupus familis XP_546136 788 88140 S478 G R A G R F S S K Y K E G E V
Cat Felis silvestris
Mouse Mus musculus Q80YD1 779 86986 S476 G R A G R F S S H F K E G Q V
Rat Rattus norvegicus Q5EBA1 776 86687 S476 G R A G R F S S H F K E G E V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZJT0 794 88758 S464 G R A G R F G S S F K Q G E V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A4IG62 763 86236 S474 G R A G R F S S V F K E G E V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VN03 763 86607 T463 G R A G R F R T Q W E H G Y V
Honey Bee Apis mellifera XP_624007 726 82213 K441 I Q P T I N K K G E I D I S T
Nematode Worm Caenorhab. elegans Q17828 721 81251 S431 I R R V I F N S C T R Q T E L
Sea Urchin Strong. purpuratus XP_786336 863 97104 T512 G R A G R F R T Q F E E G E A
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001151526 727 81897 F435 L N I R R V V F Y S L A K Y N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_198800 776 88176 R476 G A L P P E T R R Q Q A K L F
Baker's Yeast Sacchar. cerevisiae P32580 737 84306 D422 L K L K I E K D T N L K V A V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 97.1 90.9 N.A. 87.7 87.9 N.A. N.A. 68.7 N.A. 67.1 N.A. 53.5 48.3 43 55.5
Protein Similarity: 100 99.7 98.7 95.1 N.A. 92.7 92.3 N.A. N.A. 80.2 N.A. 80.5 N.A. 68.8 66.1 60.4 69.9
P-Site Identity: 100 100 93.3 86.6 N.A. 86.6 93.3 N.A. N.A. 80 N.A. 93.3 N.A. 53.3 0 26.6 66.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. 86.6 N.A. 93.3 N.A. 80 13.3 53.3 86.6
Percent
Protein Identity: N.A. 34.4 N.A. 37.5 27.3 N.A.
Protein Similarity: N.A. 52.9 N.A. 57.5 45.6 N.A.
P-Site Identity: N.A. 6.6 N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. 6.6 N.A. 26.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 67 0 0 0 0 0 0 0 0 14 0 7 7 % A
% Cys: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 7 0 0 0 7 0 0 0 % D
% Glu: 0 0 0 0 0 14 0 0 0 7 14 54 0 60 0 % E
% Phe: 0 0 0 0 0 74 0 7 0 54 0 0 0 0 7 % F
% Gly: 74 0 0 67 0 0 7 0 7 0 0 0 67 0 0 % G
% His: 0 0 0 0 0 0 0 0 14 0 0 7 0 0 0 % H
% Ile: 14 0 7 0 20 0 0 0 0 0 7 0 7 0 0 % I
% Lys: 0 7 0 7 0 0 14 7 7 0 54 7 14 0 0 % K
% Leu: 14 0 14 0 0 0 0 0 0 0 14 0 0 7 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 0 0 7 7 0 0 7 0 0 0 0 7 % N
% Pro: 0 0 7 7 7 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 7 0 0 0 0 0 0 20 7 7 14 0 7 0 % Q
% Arg: 0 74 7 7 74 0 14 7 20 0 7 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 47 60 7 7 0 0 0 7 0 % S
% Thr: 0 0 0 7 0 0 7 14 7 7 0 0 7 0 7 % T
% Val: 0 0 0 7 0 7 7 0 7 0 0 0 7 0 67 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 7 7 0 0 0 14 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _