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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SUPV3L1 All Species: 23.33
Human Site: S53 Identified Species: 36.67
UniProt: Q8IYB8 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IYB8 NP_003162.2 786 87991 S53 A T A S S S A S G G S K I P N
Chimpanzee Pan troglodytes XP_521497 786 87916 S53 A T A S S S A S G G S K I P N
Rhesus Macaque Macaca mulatta XP_001110593 787 88079 S54 A T A S S S A S G G S K I P N
Dog Lupus familis XP_546136 788 88140 S55 S A S S S S A S G G S K A P N
Cat Felis silvestris
Mouse Mus musculus Q80YD1 779 86986 S53 L A A S S S A S G G S K A P N
Rat Rattus norvegicus Q5EBA1 776 86687 S53 L A A S S S A S G G S K A P N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZJT0 794 88758 P54 P D T S L F V P V P L K P V E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A4IG62 763 86236 S51 K L S T R H S S S G S S R P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VN03 763 86607 Q57 S T L F K P V Q V H A Y V D S
Honey Bee Apis mellifera XP_624007 726 82213 N44 T Y L K K T Q N N L K I K E S
Nematode Worm Caenorhab. elegans Q17828 721 81251 I49 S V R K T A T I E D I V E P R
Sea Urchin Strong. purpuratus XP_786336 863 97104 S87 S G I R R S F S D K D D K N V
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001151526 727 81897 A52 F F S T G E S A G D P T Q K P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_198800 776 88176 C50 D V P T N R F C S G N R V R I
Baker's Yeast Sacchar. cerevisiae P32580 737 84306 K48 D W I V K R P K F L N L P K N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 97.1 90.9 N.A. 87.7 87.9 N.A. N.A. 68.7 N.A. 67.1 N.A. 53.5 48.3 43 55.5
Protein Similarity: 100 99.7 98.7 95.1 N.A. 92.7 92.3 N.A. N.A. 80.2 N.A. 80.5 N.A. 68.8 66.1 60.4 69.9
P-Site Identity: 100 100 100 73.3 N.A. 80 80 N.A. N.A. 13.3 N.A. 26.6 N.A. 6.6 0 6.6 13.3
P-Site Similarity: 100 100 100 86.6 N.A. 80 80 N.A. N.A. 13.3 N.A. 46.6 N.A. 33.3 20 26.6 20
Percent
Protein Identity: N.A. 34.4 N.A. 37.5 27.3 N.A.
Protein Similarity: N.A. 52.9 N.A. 57.5 45.6 N.A.
P-Site Identity: N.A. 6.6 N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. 33.3 N.A. 40 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 20 34 0 0 7 40 7 0 0 7 0 20 0 0 % A
% Cys: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % C
% Asp: 14 7 0 0 0 0 0 0 7 14 7 7 0 7 0 % D
% Glu: 0 0 0 0 0 7 0 0 7 0 0 0 7 7 7 % E
% Phe: 7 7 0 7 0 7 14 0 7 0 0 0 0 0 0 % F
% Gly: 0 7 0 0 7 0 0 0 47 54 0 0 0 0 0 % G
% His: 0 0 0 0 0 7 0 0 0 7 0 0 0 0 0 % H
% Ile: 0 0 14 0 0 0 0 7 0 0 7 7 20 0 7 % I
% Lys: 7 0 0 14 20 0 0 7 0 7 7 47 14 14 0 % K
% Leu: 14 7 14 0 7 0 0 0 0 14 7 7 0 0 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 7 0 0 7 7 0 14 0 0 7 47 % N
% Pro: 7 0 7 0 0 7 7 7 0 7 7 0 14 54 7 % P
% Gln: 0 0 0 0 0 0 7 7 0 0 0 0 7 0 0 % Q
% Arg: 0 0 7 7 14 14 0 0 0 0 0 7 7 7 7 % R
% Ser: 27 0 20 47 40 47 14 54 14 0 47 7 0 0 14 % S
% Thr: 7 27 7 20 7 7 7 0 0 0 0 7 0 0 0 % T
% Val: 0 14 0 7 0 0 14 0 14 0 0 7 14 7 7 % V
% Trp: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 0 0 0 0 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _