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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SUPV3L1 All Species: 27.27
Human Site: S589 Identified Species: 42.86
UniProt: Q8IYB8 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IYB8 NP_003162.2 786 87991 S589 K Q P F V C S S L L Q F A R Q
Chimpanzee Pan troglodytes XP_521497 786 87916 S589 K Q P F V C S S L L Q F A R Q
Rhesus Macaque Macaca mulatta XP_001110593 787 88079 S590 K Q P F V C S S L L Q F A R Q
Dog Lupus familis XP_546136 788 88140 S591 K Q P F V C S S L L Q F A R Q
Cat Felis silvestris
Mouse Mus musculus Q80YD1 779 86986 S589 K Q P F V C S S L L Q F A R Q
Rat Rattus norvegicus Q5EBA1 776 86687 S589 K Q P F V C S S L L Q F A R Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZJT0 794 88758 T577 K E P F V C T T L L K F A R Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A4IG62 763 86236 F583 P I N K K Q P F V C T S F L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VN03 763 86607 M577 K M P F V C S M F L K V A R Q
Honey Bee Apis mellifera XP_624007 726 82213 L548 N L D D F K F L A D M I Q H I
Nematode Worm Caenorhab. elegans Q17828 721 81251 A538 V Y D M R E L A V L I D Q I P
Sea Urchin Strong. purpuratus XP_786336 863 97104 M625 K L P F I C T M F L K F A R Q
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001151526 727 81897 D542 T Y F M C Q Q D S I K K V A N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_198800 776 88176 I584 L F P F F E Q I E L F A A Q V
Baker's Yeast Sacchar. cerevisiae P32580 737 84306 E532 K S V R K A I E A P V E Y L K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 97.1 90.9 N.A. 87.7 87.9 N.A. N.A. 68.7 N.A. 67.1 N.A. 53.5 48.3 43 55.5
Protein Similarity: 100 99.7 98.7 95.1 N.A. 92.7 92.3 N.A. N.A. 80.2 N.A. 80.5 N.A. 68.8 66.1 60.4 69.9
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 73.3 N.A. 0 N.A. 66.6 0 6.6 60
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 N.A. 13.3 N.A. 73.3 0 20 80
Percent
Protein Identity: N.A. 34.4 N.A. 37.5 27.3 N.A.
Protein Similarity: N.A. 52.9 N.A. 57.5 45.6 N.A.
P-Site Identity: N.A. 0 N.A. 26.6 6.6 N.A.
P-Site Similarity: N.A. 13.3 N.A. 33.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 7 0 7 14 0 0 7 67 7 0 % A
% Cys: 0 0 0 0 7 60 0 0 0 7 0 0 0 0 0 % C
% Asp: 0 0 14 7 0 0 0 7 0 7 0 7 0 0 0 % D
% Glu: 0 7 0 0 0 14 0 7 7 0 0 7 0 0 0 % E
% Phe: 0 7 7 67 14 0 7 7 14 0 7 54 7 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % H
% Ile: 0 7 0 0 7 0 7 7 0 7 7 7 0 7 7 % I
% Lys: 67 0 0 7 14 7 0 0 0 0 27 7 0 0 14 % K
% Leu: 7 14 0 0 0 0 7 7 47 74 0 0 0 14 0 % L
% Met: 0 7 0 14 0 0 0 14 0 0 7 0 0 0 0 % M
% Asn: 7 0 7 0 0 0 0 0 0 0 0 0 0 0 7 % N
% Pro: 7 0 67 0 0 0 7 0 0 7 0 0 0 0 7 % P
% Gln: 0 40 0 0 0 14 14 0 0 0 40 0 14 7 60 % Q
% Arg: 0 0 0 7 7 0 0 0 0 0 0 0 0 60 0 % R
% Ser: 0 7 0 0 0 0 47 40 7 0 0 7 0 0 0 % S
% Thr: 7 0 0 0 0 0 14 7 0 0 7 0 0 0 0 % T
% Val: 7 0 7 0 54 0 0 0 14 0 7 7 7 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 14 0 0 0 0 0 0 0 0 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _