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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SUPV3L1 All Species: 12.42
Human Site: S725 Identified Species: 19.52
UniProt: Q8IYB8 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IYB8 NP_003162.2 786 87991 S725 S K A T E P P S P D A G E L S
Chimpanzee Pan troglodytes XP_521497 786 87916 S725 S K A T E P P S P D A G E L S
Rhesus Macaque Macaca mulatta XP_001110593 787 88079 S726 S K A T E P P S A N A G E L S
Dog Lupus familis XP_546136 788 88140 T727 S K A T E P P T S N A E E K S
Cat Felis silvestris
Mouse Mus musculus Q80YD1 779 86986 K719 G T K S A G N K A T E P L S P
Rat Rattus norvegicus Q5EBA1 776 86687 N715 T R G T K T G N K A A E P P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZJT0 794 88758 D734 R S A T R Q E D L K S H G R G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A4IG62 763 86236 K702 E S E T S Q R K G R V L R S Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VN03 763 86607 E702 L S R G R L T E R L L A Q G L
Honey Bee Apis mellifera XP_624007 726 82213 G666 K G I K K I T G L F Q K S K T
Nematode Worm Caenorhab. elegans Q17828 721 81251 L657 V E S F M S L L S V G A T E S
Sea Urchin Strong. purpuratus XP_786336 863 97104 P778 S P R Q R H Q P L E G E G P S
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001151526 727 81897 A660 L G K S L A K A C W K P E S R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_198800 776 88176 F714 Q F E E N F P F V E K V E A M
Baker's Yeast Sacchar. cerevisiae P32580 737 84306 C655 F N L L D Y N C I P N E S Y S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 97.1 90.9 N.A. 87.7 87.9 N.A. N.A. 68.7 N.A. 67.1 N.A. 53.5 48.3 43 55.5
Protein Similarity: 100 99.7 98.7 95.1 N.A. 92.7 92.3 N.A. N.A. 80.2 N.A. 80.5 N.A. 68.8 66.1 60.4 69.9
P-Site Identity: 100 100 86.6 66.6 N.A. 0 20 N.A. N.A. 13.3 N.A. 6.6 N.A. 0 0 6.6 13.3
P-Site Similarity: 100 100 93.3 80 N.A. 6.6 46.6 N.A. N.A. 20 N.A. 6.6 N.A. 6.6 13.3 20 20
Percent
Protein Identity: N.A. 34.4 N.A. 37.5 27.3 N.A.
Protein Similarity: N.A. 52.9 N.A. 57.5 45.6 N.A.
P-Site Identity: N.A. 6.6 N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. 20 N.A. 20 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 34 0 7 7 0 7 14 7 34 14 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 7 7 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 7 0 0 7 0 14 0 0 0 0 0 % D
% Glu: 7 7 14 7 27 0 7 7 0 14 7 27 40 7 0 % E
% Phe: 7 7 0 7 0 7 0 7 0 7 0 0 0 0 0 % F
% Gly: 7 14 7 7 0 7 7 7 7 0 14 20 14 7 7 % G
% His: 0 0 0 0 0 7 0 0 0 0 0 7 0 0 0 % H
% Ile: 0 0 7 0 0 7 0 0 7 0 0 0 0 0 0 % I
% Lys: 7 27 14 7 14 0 7 14 7 7 14 7 0 14 0 % K
% Leu: 14 0 7 7 7 7 7 7 20 7 7 7 7 20 7 % L
% Met: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 7 % M
% Asn: 0 7 0 0 7 0 14 7 0 14 7 0 0 0 0 % N
% Pro: 0 7 0 0 0 27 34 7 14 7 0 14 7 14 7 % P
% Gln: 7 0 0 7 0 14 7 0 0 0 7 0 7 0 7 % Q
% Arg: 7 7 14 0 20 0 7 0 7 7 0 0 7 7 7 % R
% Ser: 34 20 7 14 7 7 0 20 14 0 7 0 14 20 54 % S
% Thr: 7 7 0 47 0 7 14 7 0 7 0 0 7 0 7 % T
% Val: 7 0 0 0 0 0 0 0 7 7 7 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 7 0 0 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _