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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SUPV3L1 All Species: 38.18
Human Site: Y345 Identified Species: 60
UniProt: Q8IYB8 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IYB8 NP_003162.2 786 87991 Y345 E E V E V R D Y K R L T P I S
Chimpanzee Pan troglodytes XP_521497 786 87916 Y345 E E V E V R D Y K R L T P I S
Rhesus Macaque Macaca mulatta XP_001110593 787 88079 Y346 E E V E V R D Y K R L T P I S
Dog Lupus familis XP_546136 788 88140 Y347 E E V E V R N Y K R L T P I S
Cat Felis silvestris
Mouse Mus musculus Q80YD1 779 86986 Y345 E E V E V Q K Y E R L T P I S
Rat Rattus norvegicus Q5EBA1 776 86687 Y345 E E V E V Q K Y E R L T P I S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZJT0 794 88758 Y333 E E V E V R N Y K R L T P L T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A4IG62 763 86236 Y343 E E V E V H N Y K R L T P F S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VN03 763 86607 Y332 E T V E V R L Y D R L T E L T
Honey Bee Apis mellifera XP_624007 726 82213 I316 L C G E S A A I P I I Q S I C
Nematode Worm Caenorhab. elegans Q17828 721 81251 L299 W A W T R A L L G A A A D E I
Sea Urchin Strong. purpuratus XP_786336 863 97104 Y381 D E L E I R E Y K R L T P L Q
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001151526 727 81897 I310 L G L K A D E I H L C G D P S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_198800 776 88176 A339 E K K Y V P F A N H V S C T V
Baker's Yeast Sacchar. cerevisiae P32580 737 84306 D296 E E V I R D L D D R G N S A G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 97.1 90.9 N.A. 87.7 87.9 N.A. N.A. 68.7 N.A. 67.1 N.A. 53.5 48.3 43 55.5
Protein Similarity: 100 99.7 98.7 95.1 N.A. 92.7 92.3 N.A. N.A. 80.2 N.A. 80.5 N.A. 68.8 66.1 60.4 69.9
P-Site Identity: 100 100 100 93.3 N.A. 80 80 N.A. N.A. 80 N.A. 80 N.A. 60 13.3 0 60
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. 100 N.A. 86.6 N.A. 73.3 20 0 93.3
Percent
Protein Identity: N.A. 34.4 N.A. 37.5 27.3 N.A.
Protein Similarity: N.A. 52.9 N.A. 57.5 45.6 N.A.
P-Site Identity: N.A. 6.6 N.A. 13.3 26.6 N.A.
P-Site Similarity: N.A. 26.6 N.A. 33.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 7 14 7 7 0 7 7 7 0 7 0 % A
% Cys: 0 7 0 0 0 0 0 0 0 0 7 0 7 0 7 % C
% Asp: 7 0 0 0 0 14 20 7 14 0 0 0 14 0 0 % D
% Glu: 74 67 0 74 0 0 14 0 14 0 0 0 7 7 0 % E
% Phe: 0 0 0 0 0 0 7 0 0 0 0 0 0 7 0 % F
% Gly: 0 7 7 0 0 0 0 0 7 0 7 7 0 0 7 % G
% His: 0 0 0 0 0 7 0 0 7 7 0 0 0 0 0 % H
% Ile: 0 0 0 7 7 0 0 14 0 7 7 0 0 47 7 % I
% Lys: 0 7 7 7 0 0 14 0 47 0 0 0 0 0 0 % K
% Leu: 14 0 14 0 0 0 20 7 0 7 67 0 0 20 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 20 0 7 0 0 7 0 0 0 % N
% Pro: 0 0 0 0 0 7 0 0 7 0 0 0 60 7 0 % P
% Gln: 0 0 0 0 0 14 0 0 0 0 0 7 0 0 7 % Q
% Arg: 0 0 0 0 14 47 0 0 0 74 0 0 0 0 0 % R
% Ser: 0 0 0 0 7 0 0 0 0 0 0 7 14 0 54 % S
% Thr: 0 7 0 7 0 0 0 0 0 0 0 67 0 7 14 % T
% Val: 0 0 67 0 67 0 0 0 0 0 7 0 0 0 7 % V
% Trp: 7 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 0 0 67 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _