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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHDC8A
All Species:
13.64
Human Site:
S185
Identified Species:
33.33
UniProt:
Q8IYD2
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYD2
NP_060673.1
350
38859
S185
Y
V
L
G
G
R
Q
S
K
Y
A
V
N
A
F
Chimpanzee
Pan troglodytes
XP_526201
354
37630
G185
Y
V
L
G
G
R
Q
G
K
L
P
V
T
A
F
Rhesus Macaque
Macaca mulatta
XP_001093425
350
38667
S185
Y
V
L
G
G
R
Q
S
K
Y
A
V
N
A
F
Dog
Lupus familis
XP_545688
350
38753
S185
Y
V
L
G
G
R
Q
S
K
Y
A
V
N
A
F
Cat
Felis silvestris
Mouse
Mus musculus
Q91XA8
350
38798
S185
Y
V
L
G
G
R
Q
S
K
Y
A
V
N
A
F
Rat
Rattus norvegicus
Q5XIA9
354
37575
G185
Y
V
L
G
G
R
Q
G
K
L
P
V
T
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520132
224
25005
F69
A
V
N
A
F
E
V
F
D
I
E
T
R
S
W
Chicken
Gallus gallus
XP_417963
313
34598
D158
I
N
A
F
E
V
F
D
T
E
T
R
S
W
T
Frog
Xenopus laevis
NP_001085780
350
38644
A185
Y
V
L
G
G
R
Q
A
K
Y
A
V
N
A
F
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789836
374
40439
G194
Y
V
L
G
G
R
N
G
K
Y
P
V
M
C
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.7
98.8
94.8
N.A.
95.7
46
N.A.
60
76.2
72.8
N.A.
N.A.
N.A.
N.A.
N.A.
31.8
Protein Similarity:
100
64.1
99.4
98.2
N.A.
97.7
63.8
N.A.
63.1
82.8
85.4
N.A.
N.A.
N.A.
N.A.
N.A.
50
P-Site Identity:
100
73.3
100
100
N.A.
100
73.3
N.A.
6.6
0
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
60
P-Site Similarity:
100
73.3
100
100
N.A.
100
73.3
N.A.
20
6.6
100
N.A.
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
10
0
0
0
10
0
0
50
0
0
70
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
10
0
0
0
10
10
0
0
0
0
% E
% Phe:
0
0
0
10
10
0
10
10
0
0
0
0
0
0
70
% F
% Gly:
0
0
0
80
80
0
0
30
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
80
0
0
0
0
0
0
% K
% Leu:
0
0
80
0
0
0
0
0
0
20
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
10
10
0
0
0
10
0
0
0
0
0
50
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
30
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
70
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
80
0
0
0
0
0
10
10
0
0
% R
% Ser:
0
0
0
0
0
0
0
40
0
0
0
0
10
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
10
0
10
10
20
0
10
% T
% Val:
0
90
0
0
0
10
10
0
0
0
0
80
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% W
% Tyr:
80
0
0
0
0
0
0
0
0
60
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _