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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHDC8A
All Species:
23.03
Human Site:
S261
Identified Species:
56.3
UniProt:
Q8IYD2
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYD2
NP_060673.1
350
38859
S261
G
W
L
K
M
E
R
S
F
F
L
K
K
R
R
Chimpanzee
Pan troglodytes
XP_526201
354
37630
S264
S
W
T
K
L
P
R
S
L
R
M
R
D
K
R
Rhesus Macaque
Macaca mulatta
XP_001093425
350
38667
S261
G
W
L
K
M
E
R
S
F
F
L
K
K
R
R
Dog
Lupus familis
XP_545688
350
38753
S261
G
W
L
K
M
E
R
S
F
F
L
K
K
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q91XA8
350
38798
S261
G
W
L
K
M
E
R
S
F
F
L
K
K
R
R
Rat
Rattus norvegicus
Q5XIA9
354
37575
S264
S
W
T
K
L
P
R
S
L
R
M
R
D
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520132
224
25005
A143
F
F
L
K
K
R
R
A
D
F
V
A
G
S
L
Chicken
Gallus gallus
XP_417963
313
34598
D232
Y
L
K
K
R
R
A
D
F
V
A
G
Y
L
K
Frog
Xenopus laevis
NP_001085780
350
38644
S261
G
W
M
K
T
E
R
S
C
F
L
R
K
R
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789836
374
40439
C274
P
H
V
R
G
D
F
C
A
G
M
V
A
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.7
98.8
94.8
N.A.
95.7
46
N.A.
60
76.2
72.8
N.A.
N.A.
N.A.
N.A.
N.A.
31.8
Protein Similarity:
100
64.1
99.4
98.2
N.A.
97.7
63.8
N.A.
63.1
82.8
85.4
N.A.
N.A.
N.A.
N.A.
N.A.
50
P-Site Identity:
100
33.3
100
100
N.A.
100
33.3
N.A.
26.6
13.3
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
60
100
100
N.A.
100
60
N.A.
46.6
20
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
10
10
0
10
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
10
10
0
0
0
20
0
0
% D
% Glu:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% E
% Phe:
10
10
0
0
0
0
10
0
50
60
0
0
0
0
0
% F
% Gly:
50
0
0
0
10
0
0
0
0
10
0
10
10
10
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
90
10
0
0
0
0
0
0
40
50
20
20
% K
% Leu:
0
10
50
0
20
0
0
0
20
0
50
0
0
10
10
% L
% Met:
0
0
10
0
40
0
0
0
0
0
30
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
10
20
80
0
0
20
0
30
0
50
70
% R
% Ser:
20
0
0
0
0
0
0
70
0
0
0
0
0
10
0
% S
% Thr:
0
0
20
0
10
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
0
10
10
10
0
0
0
% V
% Trp:
0
70
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _