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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHDC8A
All Species:
23.33
Human Site:
Y130
Identified Species:
57.04
UniProt:
Q8IYD2
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYD2
NP_060673.1
350
38859
Y130
T
A
K
D
Y
R
V
Y
A
A
G
G
M
G
L
Chimpanzee
Pan troglodytes
XP_526201
354
37630
Y130
V
E
R
D
G
M
V
Y
A
L
G
G
M
G
P
Rhesus Macaque
Macaca mulatta
XP_001093425
350
38667
Y130
T
A
K
D
Y
R
V
Y
A
A
G
G
M
G
L
Dog
Lupus familis
XP_545688
350
38753
Y130
T
A
K
D
Y
R
V
Y
A
A
G
G
M
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q91XA8
350
38798
Y130
T
A
K
D
Y
R
V
Y
A
A
G
G
M
G
L
Rat
Rattus norvegicus
Q5XIA9
354
37575
Y130
V
E
R
D
G
M
V
Y
A
L
G
G
M
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520132
224
25005
N17
G
L
D
L
R
P
H
N
Y
L
Q
H
Y
D
M
Chicken
Gallus gallus
XP_417963
313
34598
Y106
A
D
L
R
P
H
N
Y
L
Q
H
Y
D
M
L
Frog
Xenopus laevis
NP_001085780
350
38644
Y130
S
V
R
D
C
R
V
Y
A
A
G
G
M
G
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789836
374
40439
V138
T
V
V
H
N
G
K
V
I
T
I
G
G
M
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.7
98.8
94.8
N.A.
95.7
46
N.A.
60
76.2
72.8
N.A.
N.A.
N.A.
N.A.
N.A.
31.8
Protein Similarity:
100
64.1
99.4
98.2
N.A.
97.7
63.8
N.A.
63.1
82.8
85.4
N.A.
N.A.
N.A.
N.A.
N.A.
50
P-Site Identity:
100
53.3
100
100
N.A.
100
53.3
N.A.
0
13.3
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
60
100
100
N.A.
100
60
N.A.
6.6
13.3
80
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
40
0
0
0
0
0
0
70
50
0
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
70
0
0
0
0
0
0
0
0
10
10
0
% D
% Glu:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
20
10
0
0
0
0
70
80
10
70
0
% G
% His:
0
0
0
10
0
10
10
0
0
0
10
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% I
% Lys:
0
0
40
0
0
0
10
0
0
0
0
0
0
0
10
% K
% Leu:
0
10
10
10
0
0
0
0
10
30
0
0
0
0
50
% L
% Met:
0
0
0
0
0
20
0
0
0
0
0
0
70
20
10
% M
% Asn:
0
0
0
0
10
0
10
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
20
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% Q
% Arg:
0
0
30
10
10
50
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% S
% Thr:
50
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% T
% Val:
20
20
10
0
0
0
70
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
40
0
0
80
10
0
0
10
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _