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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FANCM
All Species:
9.09
Human Site:
S1286
Identified Species:
25
UniProt:
Q8IYD8
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYD8
NP_065988.1
2048
232191
S1286
A
L
I
P
R
D
H
S
K
N
F
T
S
G
T
Chimpanzee
Pan troglodytes
XP_509928
2048
232151
S1286
A
L
I
P
R
D
H
S
K
N
F
T
S
G
T
Rhesus Macaque
Macaca mulatta
XP_001096802
2050
232308
S1287
A
L
I
P
R
D
H
S
K
N
F
T
S
G
T
Dog
Lupus familis
XP_537429
2047
232355
V1286
A
V
I
P
Q
D
H
V
A
G
F
T
S
R
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGE5
2021
225999
H1252
A
A
D
V
S
G
R
H
S
D
K
E
I
K
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001171151
2166
244429
D1386
D
D
E
L
S
E
S
D
S
I
I
E
T
P
S
Zebra Danio
Brachydanio rerio
NP_001107132
1761
197421
G1025
G
S
R
L
N
I
T
G
P
D
G
E
H
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781239
2463
274499
G1479
A
R
E
A
A
A
F
G
D
E
I
H
A
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_174785
1324
148336
E588
K
P
E
V
Q
H
V
E
F
S
I
K
Q
F
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
94.2
79.4
N.A.
65.2
N.A.
N.A.
N.A.
N.A.
44
38
N.A.
N.A.
N.A.
N.A.
31.2
Protein Similarity:
100
99.2
96.6
87.5
N.A.
76.2
N.A.
N.A.
N.A.
N.A.
60.1
55.4
N.A.
N.A.
N.A.
N.A.
49.1
P-Site Identity:
100
100
100
60
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
73.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
20
6.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
67
12
0
12
12
12
0
0
12
0
0
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
12
12
0
0
45
0
12
12
23
0
0
0
0
12
% D
% Glu:
0
0
34
0
0
12
0
12
0
12
0
34
0
0
23
% E
% Phe:
0
0
0
0
0
0
12
0
12
0
45
0
0
12
0
% F
% Gly:
12
0
0
0
0
12
0
23
0
12
12
0
0
34
0
% G
% His:
0
0
0
0
0
12
45
12
0
0
0
12
12
0
0
% H
% Ile:
0
0
45
0
0
12
0
0
0
12
34
0
12
0
0
% I
% Lys:
12
0
0
0
0
0
0
0
34
0
12
12
0
12
0
% K
% Leu:
0
34
0
23
0
0
0
0
0
0
0
0
0
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
12
0
0
0
0
34
0
0
0
0
0
% N
% Pro:
0
12
0
45
0
0
0
0
12
0
0
0
0
12
0
% P
% Gln:
0
0
0
0
23
0
0
0
0
0
0
0
12
0
0
% Q
% Arg:
0
12
12
0
34
0
12
0
0
0
0
0
0
12
0
% R
% Ser:
0
12
0
0
23
0
12
34
23
12
0
0
45
12
12
% S
% Thr:
0
0
0
0
0
0
12
0
0
0
0
45
12
0
45
% T
% Val:
0
12
0
23
0
0
12
12
0
0
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _