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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FANCM
All Species:
16.97
Human Site:
S1619
Identified Species:
46.67
UniProt:
Q8IYD8
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYD8
NP_065988.1
2048
232191
S1619
E
S
C
K
G
Q
S
S
E
E
E
V
C
V
D
Chimpanzee
Pan troglodytes
XP_509928
2048
232151
S1619
E
S
C
K
G
Q
S
S
E
E
E
V
C
V
D
Rhesus Macaque
Macaca mulatta
XP_001096802
2050
232308
S1620
E
S
C
K
G
Q
S
S
E
E
E
V
C
V
D
Dog
Lupus familis
XP_537429
2047
232355
S1618
E
S
Y
K
S
Q
S
S
E
E
E
V
C
V
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGE5
2021
225999
S1581
E
S
C
K
S
Q
S
S
E
E
E
I
S
V
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001171151
2166
244429
A1740
E
E
D
D
D
D
K
A
N
D
L
E
S
S
E
Zebra Danio
Brachydanio rerio
NP_001107132
1761
197421
G1343
E
Q
N
Q
S
L
Q
G
F
V
V
N
N
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781239
2463
274499
G1864
E
E
E
E
E
D
Q
G
M
R
E
D
I
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_174785
1324
148336
E906
A
N
R
E
E
D
L
E
F
P
Q
L
S
S
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
94.2
79.4
N.A.
65.2
N.A.
N.A.
N.A.
N.A.
44
38
N.A.
N.A.
N.A.
N.A.
31.2
Protein Similarity:
100
99.2
96.6
87.5
N.A.
76.2
N.A.
N.A.
N.A.
N.A.
60.1
55.4
N.A.
N.A.
N.A.
N.A.
49.1
P-Site Identity:
100
100
100
86.6
N.A.
80
N.A.
N.A.
N.A.
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
26.6
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% A
% Cys:
0
0
45
0
0
0
0
0
0
0
0
0
45
0
0
% C
% Asp:
0
0
12
12
12
34
0
0
0
12
0
12
0
0
56
% D
% Glu:
89
23
12
23
23
0
0
12
56
56
67
12
0
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
23
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
34
0
0
23
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
12
12
0
0
% I
% Lys:
0
0
0
56
0
0
12
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
12
12
0
0
0
12
12
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% M
% Asn:
0
12
12
0
0
0
0
0
12
0
0
12
12
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
12
% P
% Gln:
0
12
0
12
0
56
23
0
0
0
12
0
0
0
12
% Q
% Arg:
0
0
12
0
0
0
0
0
0
12
0
0
0
0
0
% R
% Ser:
0
56
0
0
34
0
56
56
0
0
0
0
34
34
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% T
% Val:
0
0
0
0
0
0
0
0
0
12
12
45
0
56
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _