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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FANCM
All Species:
13.64
Human Site:
S250
Identified Species:
37.5
UniProt:
Q8IYD8
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYD8
NP_065988.1
2048
232191
S250
A
L
S
A
T
P
G
S
D
I
K
A
V
Q
Q
Chimpanzee
Pan troglodytes
XP_509928
2048
232151
S250
A
L
T
A
T
P
G
S
D
I
K
A
V
Q
Q
Rhesus Macaque
Macaca mulatta
XP_001096802
2050
232308
S250
A
L
S
A
T
P
G
S
D
I
K
A
V
Q
Q
Dog
Lupus familis
XP_537429
2047
232355
S250
A
L
S
A
T
P
G
S
D
I
K
A
I
Q
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGE5
2021
225999
K241
A
T
P
G
S
D
I
K
A
V
Q
Q
V
I
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001171151
2166
244429
G352
A
L
S
A
T
P
G
G
D
T
K
S
V
Q
Q
Zebra Danio
Brachydanio rerio
NP_001107132
1761
197421
L45
D
D
D
D
D
D
V
L
L
V
A
V
C
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781239
2463
274499
Q269
P
L
G
D
E
L
K
Q
V
K
E
Q
Y
L
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_174785
1324
148336
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
94.2
79.4
N.A.
65.2
N.A.
N.A.
N.A.
N.A.
44
38
N.A.
N.A.
N.A.
N.A.
31.2
Protein Similarity:
100
99.2
96.6
87.5
N.A.
76.2
N.A.
N.A.
N.A.
N.A.
60.1
55.4
N.A.
N.A.
N.A.
N.A.
49.1
P-Site Identity:
100
93.3
100
93.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
80
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
86.6
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
67
0
0
56
0
0
0
0
12
0
12
45
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% C
% Asp:
12
12
12
23
12
23
0
0
56
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
12
0
0
0
0
0
12
0
0
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
12
12
0
0
56
12
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
12
0
0
45
0
0
12
12
0
% I
% Lys:
0
0
0
0
0
0
12
12
0
12
56
0
0
0
0
% K
% Leu:
0
67
0
0
0
12
0
12
12
0
0
0
0
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
0
12
0
0
56
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
12
0
0
12
23
0
56
67
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
45
0
12
0
0
45
0
0
0
12
0
0
0
% S
% Thr:
0
12
12
0
56
0
0
0
0
12
0
0
0
0
12
% T
% Val:
0
0
0
0
0
0
12
0
12
23
0
12
56
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _