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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FANCM
All Species:
2.42
Human Site:
T1170
Identified Species:
6.67
UniProt:
Q8IYD8
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYD8
NP_065988.1
2048
232191
T1170
D
K
T
A
I
S
E
T
P
L
V
S
Q
F
L
Chimpanzee
Pan troglodytes
XP_509928
2048
232151
M1170
D
K
T
A
I
S
E
M
P
L
V
S
Q
F
L
Rhesus Macaque
Macaca mulatta
XP_001096802
2050
232308
I1170
D
K
T
A
I
S
E
I
P
L
V
S
Q
F
L
Dog
Lupus familis
XP_537429
2047
232355
M1168
G
K
T
A
V
S
E
M
A
L
D
S
Q
F
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGE5
2021
225999
N1139
G
A
S
L
P
P
F
N
S
I
S
Q
P
L
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001171151
2166
244429
A1271
G
D
T
E
G
S
C
A
K
N
E
N
H
N
I
Zebra Danio
Brachydanio rerio
NP_001107132
1761
197421
S915
D
T
G
V
C
A
Q
S
T
A
P
S
A
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781239
2463
274499
S1361
Q
P
Q
L
K
H
A
S
T
G
E
N
K
I
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_174785
1324
148336
G478
I
I
F
S
N
F
R
G
S
V
R
D
I
M
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
94.2
79.4
N.A.
65.2
N.A.
N.A.
N.A.
N.A.
44
38
N.A.
N.A.
N.A.
N.A.
31.2
Protein Similarity:
100
99.2
96.6
87.5
N.A.
76.2
N.A.
N.A.
N.A.
N.A.
60.1
55.4
N.A.
N.A.
N.A.
N.A.
49.1
P-Site Identity:
100
93.3
93.3
66.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
13.3
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
93.3
93.3
73.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
26.6
33.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
45
0
12
12
12
12
12
0
0
12
12
12
% A
% Cys:
0
0
0
0
12
0
12
0
0
0
0
0
0
0
0
% C
% Asp:
45
12
0
0
0
0
0
0
0
0
12
12
0
0
0
% D
% Glu:
0
0
0
12
0
0
45
0
0
0
23
0
0
0
0
% E
% Phe:
0
0
12
0
0
12
12
0
0
0
0
0
0
45
0
% F
% Gly:
34
0
12
0
12
0
0
12
0
12
0
0
0
0
0
% G
% His:
0
0
0
0
0
12
0
0
0
0
0
0
12
0
0
% H
% Ile:
12
12
0
0
34
0
0
12
0
12
0
0
12
12
12
% I
% Lys:
0
45
0
0
12
0
0
0
12
0
0
0
12
0
12
% K
% Leu:
0
0
0
23
0
0
0
0
0
45
0
0
0
12
45
% L
% Met:
0
0
0
0
0
0
0
23
0
0
0
0
0
12
0
% M
% Asn:
0
0
0
0
12
0
0
12
0
12
0
23
0
12
12
% N
% Pro:
0
12
0
0
12
12
0
0
34
0
12
0
12
0
0
% P
% Gln:
12
0
12
0
0
0
12
0
0
0
0
12
45
0
0
% Q
% Arg:
0
0
0
0
0
0
12
0
0
0
12
0
0
0
12
% R
% Ser:
0
0
12
12
0
56
0
23
23
0
12
56
0
0
0
% S
% Thr:
0
12
56
0
0
0
0
12
23
0
0
0
0
0
0
% T
% Val:
0
0
0
12
12
0
0
0
0
12
34
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _