KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC146
All Species:
12.73
Human Site:
S272
Identified Species:
35
UniProt:
Q8IYE0
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYE0
NP_065930.2
955
112806
S272
E
V
K
T
L
N
D
S
L
K
K
V
E
N
K
Chimpanzee
Pan troglodytes
XP_519167
955
112923
S272
E
V
K
T
L
N
D
S
L
K
K
V
E
N
K
Rhesus Macaque
Macaca mulatta
XP_001083560
850
101055
V246
I
V
E
E
K
E
N
V
I
K
E
V
E
G
K
Dog
Lupus familis
XP_852499
956
112901
S273
E
L
K
E
L
N
D
S
L
K
K
V
E
T
K
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q66H60
974
114627
S291
E
L
K
E
L
S
D
S
L
K
K
L
E
N
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507522
927
109406
A245
Q
V
Q
E
L
N
V
A
L
K
K
V
E
N
K
Chicken
Gallus gallus
XP_415968
920
107917
L265
E
L
D
G
K
R
A
L
L
E
S
K
E
Q
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001076522
860
100875
R250
Q
L
R
K
E
V
D
R
V
A
H
K
K
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794541
712
83971
M209
K
R
Q
I
D
L
E
M
K
E
L
E
S
E
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
86.1
87.5
N.A.
N.A.
76.2
N.A.
67.6
47.3
N.A.
35.5
N.A.
N.A.
N.A.
N.A.
32.7
Protein Similarity:
100
99.7
88
94.7
N.A.
N.A.
89.6
N.A.
82.8
69.5
N.A.
58.4
N.A.
N.A.
N.A.
N.A.
50.5
P-Site Identity:
100
100
33.3
80
N.A.
N.A.
73.3
N.A.
66.6
20
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
60
86.6
N.A.
N.A.
93.3
N.A.
86.6
40
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
12
12
0
12
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
0
12
0
56
0
0
0
0
0
0
0
0
% D
% Glu:
56
0
12
45
12
12
12
0
0
23
12
12
78
12
23
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
12
0
0
0
0
0
0
0
0
0
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% H
% Ile:
12
0
0
12
0
0
0
0
12
0
0
0
0
0
0
% I
% Lys:
12
0
45
12
23
0
0
0
12
67
56
23
12
0
67
% K
% Leu:
0
45
0
0
56
12
0
12
67
0
12
12
0
0
0
% L
% Met:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
45
12
0
0
0
0
0
0
45
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
23
0
23
0
0
0
0
0
0
0
0
0
0
12
0
% Q
% Arg:
0
12
12
0
0
12
0
12
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
12
0
45
0
0
12
0
12
12
0
% S
% Thr:
0
0
0
23
0
0
0
0
0
0
0
0
0
12
12
% T
% Val:
0
45
0
0
0
12
12
12
12
0
0
56
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _