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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC146
All Species:
19.09
Human Site:
S431
Identified Species:
52.5
UniProt:
Q8IYE0
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYE0
NP_065930.2
955
112806
S431
K
I
I
S
E
M
E
S
K
L
V
E
Q
Q
L
Chimpanzee
Pan troglodytes
XP_519167
955
112923
S431
K
I
I
S
E
M
E
S
K
L
V
E
Q
Q
L
Rhesus Macaque
Macaca mulatta
XP_001083560
850
101055
S387
K
I
I
S
E
M
E
S
K
L
V
E
Q
Q
L
Dog
Lupus familis
XP_852499
956
112901
T432
K
I
L
S
E
A
E
T
K
L
V
E
Q
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q66H60
974
114627
A450
R
S
L
S
E
A
E
A
K
L
V
E
Q
Q
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507522
927
109406
T404
R
L
L
T
D
V
E
T
H
L
L
E
H
C
I
Chicken
Gallus gallus
XP_415968
920
107917
A396
E
M
V
S
D
T
D
A
R
R
L
E
E
C
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001076522
860
100875
S367
Q
I
V
A
E
F
I
S
L
R
D
K
L
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794541
712
83971
V319
Y
Q
K
E
K
E
A
V
Y
M
G
D
K
A
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
86.1
87.5
N.A.
N.A.
76.2
N.A.
67.6
47.3
N.A.
35.5
N.A.
N.A.
N.A.
N.A.
32.7
Protein Similarity:
100
99.7
88
94.7
N.A.
N.A.
89.6
N.A.
82.8
69.5
N.A.
58.4
N.A.
N.A.
N.A.
N.A.
50.5
P-Site Identity:
100
100
100
80
N.A.
N.A.
60
N.A.
20
13.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
N.A.
86.6
N.A.
80
80
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
23
12
23
0
0
0
0
0
23
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
23
0
% C
% Asp:
0
0
0
0
23
0
12
0
0
0
12
12
0
0
0
% D
% Glu:
12
0
0
12
67
12
67
0
0
0
0
78
12
0
0
% E
% Phe:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
12
0
0
0
12
0
0
% H
% Ile:
0
56
34
0
0
0
12
0
0
0
0
0
0
0
34
% I
% Lys:
45
0
12
0
12
0
0
0
56
0
0
12
12
0
0
% K
% Leu:
0
12
34
0
0
0
0
0
12
67
23
0
12
0
45
% L
% Met:
0
12
0
0
0
34
0
0
0
12
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
12
12
0
0
0
0
0
0
0
0
0
0
56
56
0
% Q
% Arg:
23
0
0
0
0
0
0
0
12
23
0
0
0
0
12
% R
% Ser:
0
12
0
67
0
0
0
45
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
12
0
12
0
23
0
0
0
0
0
0
12
% T
% Val:
0
0
23
0
0
12
0
12
0
0
56
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _